Gene Symbol | Ccno |
Entrez Gene ID | 499528 |
Full Name | cyclin O |
Synonyms | RGD1565217 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ccno cDNA ORF clone
gRNAs
Gene Symbol | Ccno |
Entrez Gene ID | 499528 |
Full Name | cyclin O |
Synonyms | RGD1565217 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001109175.1 | NP_001102645.1 | cyclin-O |
XM_006231947.3 | XP_006232009.1 | cyclin-O isoform X1 |
Canis lupus familiaris (dog) | CCNO | XP_544336.2 |
Gallus gallus (chicken) | CCNO | XP_003643032.1 |
Xenopus tropicalis (tropical clawed frog) | ccno | NP_998837.1 |
Homo sapiens (human) | CCNO | NP_066970.3 |
Pan troglodytes (chimpanzee) | CCNO | XP_001147153.1 |
Mus musculus (house mouse) | Ccno | NP_001074531.1 |
Danio rerio (zebrafish) | LOC101883490 | XP_005168712.1 |
Rattus norvegicus (Norway rat) | Ccno | NP_001102645.1 |
CCNO | XP_001098228.1 | |
Bos taurus (cattle) | CCNO | XP_002696375.1 |
Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia.
Wallmeier J, Al-Mutairi DA, Chen CT, Loges NT, Pennekamp P, Menchen T, Ma L, Shamseldin HE, Olbrich H, Dougherty GW, Werner C, Alsabah BH, K?hler G, Jaspers M, Boon M, Griese M, Schmitt-Groh? S, Zimmermann T, Koerner-Rettberg C, Horak E, Kintner C, Alkuraya FS, Omran H
Nature genetics46(6)646-51(2014 Jun)
hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup.
Kavli B, Sundheim O, Akbari M, Otterlei M, Nilsen H, Skorpen F, Aas PA, Hagen L, Krokan HE, Slupphaug G
The Journal of biological chemistry277(42)39926-36(2002 Oct)
Expression and activity of the DNA repair enzyme uracil DNA glycosylase during organogenesis in the rat conceptus and following methotrexate exposure in vitro.
Vinson RK, Hales BF
Biochemical pharmacology64(4)711-21(2002 Aug)
Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase.
Muller SJ, Caradonna S
The Journal of biological chemistry268(2)1310-9(1993 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Ccno gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccno cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa09227 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109175.1 | |
Accession Version | NM_001109175.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | cyclin-O | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473955.1. On or before Oct 4, 2007 this sequence version replaced XM_574851.2, XM_001075020.1. ##Evidence-Data-START## CDS exon combination :: BF403931.1, BF405963.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689601 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAACAGC TCCTGGCCCT GTGCGGCGGG GCTTTCTCCC GGCAGCAGCT GTGTAACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102645.1 |
CDS | 1247..1711 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAAACAGC TCCTGGCCCT GTGCGGCGGG GCTTTCTCCC GGCAGCAGCT GTGTAACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa24412 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231947.3 | |
Accession Version | XM_006231947.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | cyclin-O isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231947.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGACCC CTTGTCCTGC CAGCCCGGCC AGCCCCGCCT CGGGAGCCGG GAGGCAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006232009.1 |
CDS | 303..1361 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTGACCC CTTGTCCTGC CAGCCCGGCC AGCCCCGCCT CGGGAGCCGG GAGGCAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia. |
hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup. |
Expression and activity of the DNA repair enzyme uracil DNA glycosylase during organogenesis in the rat conceptus and following methotrexate exposure in vitro. |
Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase. |