Gene Symbol | Fancb |
Entrez Gene ID | 501552 |
Full Name | Fanconi anemia, complementation group B |
Synonyms | RGD1561555 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Fancb cDNA ORF clone
Gene Symbol | Fancb |
Entrez Gene ID | 501552 |
Full Name | Fanconi anemia, complementation group B |
Synonyms | RGD1561555 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001192003.1 | NP_001178932.1 | Fanconi anemia group B protein |
XM_006256885.3 | XP_006256947.1 | Fanconi anemia group B protein isoform X1 |
XM_008773185.2 | XP_008771407.1 | Fanconi anemia group B protein isoform X1 |
XM_017602128.1 | XP_017457617.1 | Fanconi anemia group B protein isoform X1 |
XM_006256886.3 | XP_006256948.1 | Fanconi anemia group B protein isoform X2 |
Homo sapiens (human) | FANCB | NP_001018123.1 |
FANCB | XP_002806197.1 | |
Bos taurus (cattle) | FANCB | XP_002700448.1 |
Gallus gallus (chicken) | FANCB | NP_001186029.1 |
Rattus norvegicus (Norway rat) | Fancb | NP_001178932.1 |
Danio rerio (zebrafish) | fancb | NP_001035726.1 |
Xenopus tropicalis (tropical clawed frog) | fancb | XP_004911726.1 |
Pan troglodytes (chimpanzee) | FANCB | XP_003317409.2 |
Mus musculus (house mouse) | Fancb | NP_001139553.1 |
Canis lupus familiaris (dog) | FANCB | XP_003435505.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100497907 | NP_001190183.1 |
RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.
Kim TM, Son MY, Dodds S, Hu L, Luo G, Hasty P
Nucleic acids research43(2)893-903(2015 Jan)
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
Yan Z, Delannoy M, Ling C, Daee D, Osman F, Muniandy PA, Shen X, Oostra AB, Du H, Steltenpool J, Lin T, Schuster B, D?caillet C, Stasiak A, Stasiak AZ, Stone S, Hoatlin ME, Schindler D, Woodcock CL, Joenje H, Sen R, de Winter JP, Li L, Seidman MM, Whitby MC, Myung K, Constantinou A, Wang W
Molecular cell37(6)865-78(2010 Mar)
Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers.
Smith IM, Mithani SK, Mydlarz WK, Chang SS, Califano JA
ORL; journal for oto-rhino-laryngology and its related specialties72(1)44-50(2010)
Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma.
Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ
ORL; journal for oto-rhino-laryngology and its related specialties69(4)218-25(2007)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Fancb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fancb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa08303 | |
Clone ID Related Accession (Same CDS sequence) | NM_001192003.1 , XM_006256885.3 , XM_008773185.2 , XM_017602128.1 | |
Accession Version | NM_001192003.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-02 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | Fanconi anemia group B protein | |
Comment | Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AABR07037802.1. On Jul 17, 2010 this sequence version replaced XM_576954.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689601, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001178932.1 |
CDS | 1..2562 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001192003.1 |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa08303 | |
Clone ID Related Accession (Same CDS sequence) | NM_001192003.1 , XM_006256885.3 , XM_008773185.2 , XM_017602128.1 | |
Accession Version | XM_006256885.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | Fanconi anemia group B protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256885.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006256947.1 |
CDS | 446..3007 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006256885.3 |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa08303 | |
Clone ID Related Accession (Same CDS sequence) | NM_001192003.1 , XM_006256885.3 , XM_008773185.2 , XM_017602128.1 | |
Accession Version | XM_008773185.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | Fanconi anemia group B protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773185.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008771407.1 |
CDS | 550..3111 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008773185.2 |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa08303 | |
Clone ID Related Accession (Same CDS sequence) | NM_001192003.1 , XM_006256885.3 , XM_008773185.2 , XM_017602128.1 | |
Accession Version | XM_017602128.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | Fanconi anemia group B protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017457617.1 |
CDS | 406..2967 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017602128.1 |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa39695 | |
Clone ID Related Accession (Same CDS sequence) | XM_006256886.3 | |
Accession Version | XM_006256886.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2121bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | Fanconi anemia group B protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256886.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006256948.1 |
CDS | 406..2526 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006256886.3 |
1 | ATGCCATTTA ATGAGCAAGC AAAGTTCTTG TGCTATAATG GGGAAGTCCT TGTTTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway. |
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. |
Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers. |
Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma. |