Cspg5 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Cspg5 |
| Entrez Gene ID | 50568 |
| Full Name | chondroitin sulfate proteoglycan 5 |
| Synonyms | Caleb,Ngc |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | proteoglycan expressed exclusively in brain and developing neurons [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_019284.1 | NP_062157.1 | chondroitin sulfate proteoglycan 5 isoform 1 precursor |
| NM_133652.1 | NP_598413.1 | chondroitin sulfate proteoglycan 5 isoform 2 precursor |
| Homo sapiens (human) | CSPG5 | NP_001193872.1 |
| CSPG5 | XP_001099981.2 | |
| Rattus norvegicus (Norway rat) | Cspg5 | NP_598413.1 |
| Pan troglodytes (chimpanzee) | CSPG5 | NP_001233346.1 |
| Canis lupus familiaris (dog) | CSPG5 | XP_851498.3 |
| Bos taurus (cattle) | CSPG5 | NP_001068697.1 |
| Mus musculus (house mouse) | Cspg5 | NP_001159745.1 |
Related articles in PubMed
Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity.
Schulz J, Franke K, Frick M, Schumacher S
Journal of neurochemistry139(1)26-39(2016 10)
The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity.
Brandt N, Franke K, Rasin MR, Baumgart J, Vogt J, Khrulev S, Hassel B, Pohl EE, Sestan N, Nitsch R, Schumacher S
The EMBO journal26(9)2371-86(2007 May)
Neuroglycan C is a novel midkine receptor involved in process elongation of oligodendroglial precursor-like cells.
Ichihara-Tanaka K, Oohira A, Rumsby M, Muramatsu T
The Journal of biological chemistry281(41)30857-64(2006 Oct)
Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity.
J?ttner R, Mor? MI, Das D, Babich A, Meier J, Henning M, Erdmann B, Mu Ller EC, Otto A, Grantyn R, Rathjen FG
Neuron46(2)233-45(2005 Apr)
Glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C.
Aono S, Tokita Y, Shuo T, Yamauchi S, Matsui F, Nakanishi K, Hirano K, Sano M, Oohira A
The Journal of biological chemistry279(45)46536-41(2004 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rac1, Cdc42, and RhoG perform very specific and non-redundant functions at different levels of hierarchy in regulating dendritic tree complexity induced by CALEB/NGC
Title: Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity.
PI3K-Akt-mammalian target of rapamycin (mTOR) signaling pathway and PKC are important for CALEB/NGC-induced stimulation of dendritic branching. CALEB/NGC-induced spine morphogenesis is independent of PI3K but depends on PKC.
Title: The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity.
neuroglycan C is a novel component of midkine receptors involved in process elongation
Title: Neuroglycan C is a novel midkine receptor involved in process elongation of oligodendroglial precursor-like cells.
there is a glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C
Title: Glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C.
The following Cspg5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cspg5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01097 | |
| Clone ID Related Accession (Same CDS sequence) | NM_133652.1 | |
| Accession Version | NM_133652.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | chondroitin sulfate proteoglycan 5 isoform 2 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF292102.1. On Jun 25, 2006 this sequence version replaced XM_001075674.1. Transcript Variant: This variant (2) encodes the longer isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF292102.1 [ECO:0000332] ##Evidence-Data-END## | |
1 | ATGGGCCGAG CTGGAGGCGG GGGCCCGGGC TGGGGGCCGC CGCCAGTGCT GCTGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_598413.1 |
| CDS | 1..1716 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_133652.1 |
ORF Insert Sequence:
1 | ATGGGCCGAG CTGGAGGCGG GGGCCCGGGC TGGGGGCCGC CGCCAGTGCT GCTGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa04275 | |
| Clone ID Related Accession (Same CDS sequence) | NM_019284.1 | |
| Accession Version | NM_019284.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1635bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-23 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | chondroitin sulfate proteoglycan 5 isoform 1 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U33553.1. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 2. This results in a shorter protein (isoform 1), compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U33553.1 [ECO:0000332] ##Evidence-Data-END## | |
1 | ATGGGCCGAG CTGGAGGCGG GGGCCCGGGC TGGGGGCCGC CGCCAGTGCT GCTGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_062157.1 |
| CDS | 13..1647 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_019284.1 |
ORF Insert Sequence:
1 | ATGGGCCGAG CTGGAGGCGG GGGCCCGGGC TGGGGGCCGC CGCCAGTGCT GCTGCTTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity. |
|
The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. |
|
Neuroglycan C is a novel midkine receptor involved in process elongation of oligodendroglial precursor-like cells. |
|
Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity. |
|
Glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C. |