Ptafr cDNA ORF clone, Rattus norvegicus(Norway rat)
Gene Symbol | Ptafr |
Entrez Gene ID | 58949 |
Full Name | platelet-activating factor receptor |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | acts as a receptor to mediate the biological effects of platelet-activating factor [RGD, Feb 2006]. |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_053321.2 | NP_445773.1 | platelet-activating factor receptor |
XM_006239064.2 | XP_006239126.1 | platelet-activating factor receptor isoform X1 |
XM_006239063.3 | XP_006239125.1 | platelet-activating factor receptor isoform X1 |

PTAFR | XP_001112942.2 | |
Canis lupus familiaris (dog) | PTAFR | XP_005617766.1 |
Rattus norvegicus (Norway rat) | Ptafr | NP_445773.1 |
Xenopus tropicalis (tropical clawed frog) | ptafr | NP_001008003.1 |
Homo sapiens (human) | PTAFR | NP_000943.1 |
Pan troglodytes (chimpanzee) | PTAFR | XP_001151906.1 |
Bos taurus (cattle) | PTAFR | NP_001035628.1 |
Mus musculus (house mouse) | Ptafr | NP_001074680.1 |
Danio rerio (zebrafish) | LOC100002627 | XP_001342372.1 |
Gallus gallus (chicken) | PTAFR | XP_004947758.1 |

Related articles in PubMed
PAF enhances MMP-2 production in rat aortic VSMCs via a ?-arrestin2-dependent ERK signaling pathway.
Kim YH, Lee SJ, Seo KW, Bae JU, Park SY, Kim EK, Bae SS, Kim JH, Kim CD
Journal of lipid research54(10)2678-86(2013 Oct)
Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury.
Okubo M, Yamanaka H, Kobayashi K, Kanda H, Dai Y, Noguchi K
Molecular pain88(2012 Feb)
Anti-ischaemic effects of bilobalide on neonatal rat cardiomyocytes and the involvement of the platelet-activating factor receptor.
Maerz S, Liu CH, Guo W, Zhu YZ
Bioscience reports31(5)439-47(2011 Oct)
Mechanism and dose-effect of Ginkgolide B on severe acute pancreatitis of rats.
Ji RL, Xia SH, Di Y, Xu W
World journal of gastroenterology17(17)2241-7(2011 May)
Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition.
Fragel-Madeira L, Meletti T, Mariante RM, Monteiro RQ, Einicker-Lamas M, Bernardo RR, Lopes AH, Linden R
PloS one6(1)e16058(2011 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These data show the histological localization of PAF synthases and its receptor in the spinal cord following peripheral nerve injury.
Title: Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury.
In hypoxic tissue, PAFR protein expression is up-regulated, but is reduced in the bilobalide treated tissue.
Title: Anti-ischaemic effects of bilobalide on neonatal rat cardiomyocytes and the involvement of the platelet-activating factor receptor.
PAF inhibition interkinetic nuclear migration (IKNM) in retinal proliferating progenitors depended on the PAF receptor, Erk and p38 pathways and Chk1
Title: Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition.
Cirrhosis sensitizes hepatic stellate cells to PAF by elevating its receptor level
Title: Hepatic stellate cells may be potential effectors of platelet activating factor induced portal hypertension.
Platelet activating factor receptor (PAF-R) plays an important role in occurrence and development of severe acute pancreatitis. BN52021 exerts biological effects through competitively inhibiting the binding of increased both PAF and PAF-R expression.
Title: Significance of platelet activating factor receptor expression in pancreatic tissues of rats with severe acute pancreatitis and effects of BN52021.
The following Ptafr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptafr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa09269 | |
Clone ID Related Accession (Same CDS sequence) | NM_053321.2 , XM_006239064.2 , XM_006239063.3 | |
Accession Version | NM_053321.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-23 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | platelet-activating factor receptor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC072491.1. On Jun 13, 2004 this sequence version replaced NM_053321.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC072491.1, U04740.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGCAAA ATGGCTCCTT CCGTGTGGAT TCTGAGTTTC GATACACCCT CTTTCCGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_445773.1 |
CDS | 99..1124 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGAGCAAA ATGGCTCCTT CCGTGTGGAT TCTGAGTTTC GATACACCCT CTTTCCGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa09269 | |
Clone ID Related Accession (Same CDS sequence) | NM_053321.2 , XM_006239064.2 , XM_006239063.3 | |
Accession Version | XM_006239064.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | platelet-activating factor receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006239064.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCAAA ATGGCTCCTT CCGTGTGGAT TCTGAGTTTC GATACACCCT CTTTCCGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006239126.1 |
CDS | 710..1735 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGAGCAAA ATGGCTCCTT CCGTGTGGAT TCTGAGTTTC GATACACCCT CTTTCCGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa09269 | |
Clone ID Related Accession (Same CDS sequence) | NM_053321.2 , XM_006239064.2 , XM_006239063.3 | |
Accession Version | XM_006239063.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | platelet-activating factor receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239063.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCAAA ATGGCTCCTT CCGTGTGGAT TCTGAGTTTC GATACACCCT CTTTCCGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006239125.1 |
CDS | 434..1459 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGAGCAAA ATGGCTCCTT CCGTGTGGAT TCTGAGTTTC GATACACCCT CTTTCCGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
PAF enhances MMP-2 production in rat aortic VSMCs via a ?-arrestin2-dependent ERK signaling pathway. |
![]() |
Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury. |
![]() |
Anti-ischaemic effects of bilobalide on neonatal rat cardiomyocytes and the involvement of the platelet-activating factor receptor. |
![]() |
Mechanism and dose-effect of Ginkgolide B on severe acute pancreatitis of rats. |
![]() |
Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition. |