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Card9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Card9
Entrez Gene ID 64171
Full Name caspase recruitment domain family, member 9
General protein information
Preferred Names

caspase recruitment domain family, member 9

Names

caspase recruitment domain-containing protein 9
caspase recruitment domain protein 9
rCARD9
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3p13
Summary interacts with the CARD activation domain of BCL10; activates NF-kappaB signaling [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017592019.1 XP_017447508.1 caspase recruitment domain-containing protein 9 isoform X1
XM_008761626.2 XP_008759848.1 caspase recruitment domain-containing protein 9 isoform X2
NM_022303.1 NP_071639.1 caspase recruitment domain-containing protein 9

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Card9 NP_071639.1
Xenopus tropicalis (tropical clawed frog) card9 NP_001120274.1
Pan troglodytes (chimpanzee) CARD9 XP_001171213.1
Mus musculus (house mouse) Card9 NP_001032836.1
Homo sapiens (human) CARD9 NP_434700.2
CARD9 XP_001095549.1
Danio rerio (zebrafish) card9 NP_001103755.1
Canis lupus familiaris (dog) CARD9 XP_005625174.1
Bos taurus (cattle) CARD9 NP_001070579.1
Gallus gallus (chicken) CARD9 XP_425329.4

Gene Ontology


Bibliography

Related articles in PubMed

CARD9 gene silencing with siRNA protects rats against severe acute pancreatitis: CARD9-dependent NF-?B and P38MAPKs pathway.
Yang ZW, Meng XX, Zhang C, Xu P
Journal of cellular and molecular medicine21(6)1085-1093(2017 Jun)

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens.
Hsu YM, Zhang Y, You Y, Wang D, Li H, Duramad O, Qin XF, Dong C, Lin X
Nature immunology8(2)198-205(2007 Feb)

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.
Gross O, Gewies A, Finger K, Sch?fer M, Sparwasser T, Peschel C, F?rster I, Ruland J
Nature442(7103)651-6(2006 Aug)

CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B.
Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES
The Journal of biological chemistry275(52)41082-6(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Card9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Card9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa12933 NM_022303.1
Latest version!		 Rattus norvegicus caspase recruitment domain family, member 9 (Card9), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
ORa43566 XM_017592019.1
Latest version!		 Rattus norvegicus caspase recruitment domain family, member 9 (Card9), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
ORa43567 XM_008761626.2
Latest version!		 Rattus norvegicus caspase recruitment domain family, member 9 (Card9), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa12933
Clone ID Related Accession (Same CDS sequence) NM_022303.1
Accession Version NM_022303.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1611bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-25
Organism Rattus norvegicus(Norway rat)
Product caspase recruitment domain-containing protein 9
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF311288.1. On Jan 12, 2005 this sequence version replaced XM_346649.1. ##Evidence-Data-START## Transcript exon combination :: AF311288.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGTCAGACT ATGAAAATGA CGACGAGTGC TGGAGTGCCC TGGAGAGCTT CCGGGTGAAG 
CTAATCTCTG TCATTGACCC CTCACGAATC ACACCCTATC TGCGCCAGTG CAAAGTCCTG 
AACCCCGATG ATGAGGAGCA GGTGCTCAGT GACCCCAACC TGGTCATCCG CAAGCGGAAA 
GTGGGTGTGC TCCTGGACAT CCTGCAGCGG ACAGGCCACA AGGGCTACGT GGCCTTTCTT 
GAGAGTCTGG AACTCTACTA CCCTCAGTTA TACAGGAAAG TCACTGGCAA GGAGCCAGCG 
CGTGTCTTCT CCATGATCAT CGACGCATCA GGGGAGTCGG GCCTGACGCA GCTGCTGATG 
ACAGAGGTCA TGAAGCTGCA GAAGAAGGTT CAGGACCTGA CGGCCCTTCT GAGCTCCAAG 
GATGACTTCA TCAAGGAGCT GAGGGTAAAG GACAGCCTCC TGCGCAAGCA CCAGGAGCGG 
GTGCAGCGGC TCAAGGAGGA GTGTGAGCTG AGCAGTGCCG AGCTGAAGCG CTGCAAGGAT 
GAGAACTACG ACCTGGCCAT GCGCCTGGCT CACCTGAGTG AAGAGAAGGG AGCAGCACTC 
ATGCGGAACC GTGACCTGCA GCTTGAGGTG GACCAGCTCA GGCACAGCCT CATGAAGGCA 
GAGGATGACT GCAAGGTGGA GCGCAAACAC ACACTGAAGC TCCGGCACGC CATGGAGCAG 
CGGCCTAGCC AGGAGCTGCT GTGGGACCTG CAGCAGGAGA GGGACTTGTT GCAGGCCCGG 
GTGCAGGAGC TGGAGGTCTC CGTGCAGGAG GGTAAGCTAC ACAGGAATAG CCCATACATC 
CAGGTGCTGG AGGAGGACTG GCGTCAGGCA CTGCAGGAAC ACCAGGAGCA GGCCAGCACC 
ATCTTCTCCC TACGAAAGGA CCTCCGCCAG GCTGAGGCCC TCCGGACCCG GTGCATGGAG 
GAAAAGGAGA TGTTCGAGCT GCAGTGCCTG GCCTTGCGCA AGGATGCCAA GATGTACAAG 
GACCGGATCG AGGCTATCCT GCAGCAGATG GAGGAAGTCT CCATTGAGCG GGACCAGGCT 
ATGACCTCAA GGGAAGAGCT GCATGCACAG TGTGCCCAAA GCTTTCAGGA CAAAGATAAG 
CTGCGAAAGC AGGTTCGAGA ACTGGATGAG AAGGCCGACG AGTTGCAGCT GCAGCTGTTC 
CAGACCGAGA GCCGATTACT GGCCGCTGAG GGCAGACTCA AGCAGCAGCA ATTGGACATG 
CTCATCCTGA GCTCTGACTT GGAAGACAGT TCCCCCAGGA ACTCCCAGGA GCTTTCACTG 
CCTCAGGACC TGGAGGAGGA TGCCCAGCTC TCAGACAAAG GTGTCCTGGC AGACAGGGAG 
AGCCCAGAGC AGCCCTTCGT GGTTCTGAAC AAGAAGCATC TTTCGCAGAC CCATGACACG 
GTGCCCAGCA GCAGCGAGCC CCCGGAGAAG GAGCGGCGGC GCCTCAAGGA GAGCTTCGAG 
AACTACCGCA GGAAGCGGGC GCTCCGCAAG ATGCAGAACA GCTGGCGACA GGGAGAAGGG 
GATCACGGGA ATACGACAGG CAGCGACAAC ACCGACACCG AGGGCTCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_071639.1
CDS113..1723
Translation

Target ORF information:

RefSeq Version NM_022303.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus caspase recruitment domain family, member 9 (Card9), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_022303.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGTCAGACT ATGAAAATGA CGACGAGTGC TGGAGTGCCC TGGAGAGCTT CCGGGTGAAG 
CTAATCTCTG TCATTGACCC CTCACGAATC ACACCCTATC TGCGCCAGTG CAAAGTCCTG 
AACCCCGATG ATGAGGAGCA GGTGCTCAGT GACCCCAACC TGGTCATCCG CAAGCGGAAA 
GTGGGTGTGC TCCTGGACAT CCTGCAGCGG ACAGGCCACA AGGGCTACGT GGCCTTTCTT 
GAGAGTCTGG AACTCTACTA CCCTCAGTTA TACAGGAAAG TCACTGGCAA GGAGCCAGCG 
CGTGTCTTCT CCATGATCAT CGACGCATCA GGGGAGTCGG GCCTGACGCA GCTGCTGATG 
ACAGAGGTCA TGAAGCTGCA GAAGAAGGTT CAGGACCTGA CGGCCCTTCT GAGCTCCAAG 
GATGACTTCA TCAAGGAGCT GAGGGTAAAG GACAGCCTCC TGCGCAAGCA CCAGGAGCGG 
GTGCAGCGGC TCAAGGAGGA GTGTGAGCTG AGCAGTGCCG AGCTGAAGCG CTGCAAGGAT 
GAGAACTACG ACCTGGCCAT GCGCCTGGCT CACCTGAGTG AAGAGAAGGG AGCAGCACTC 
ATGCGGAACC GTGACCTGCA GCTTGAGGTG GACCAGCTCA GGCACAGCCT CATGAAGGCA 
GAGGATGACT GCAAGGTGGA GCGCAAACAC ACACTGAAGC TCCGGCACGC CATGGAGCAG 
CGGCCTAGCC AGGAGCTGCT GTGGGACCTG CAGCAGGAGA GGGACTTGTT GCAGGCCCGG 
GTGCAGGAGC TGGAGGTCTC CGTGCAGGAG GGTAAGCTAC ACAGGAATAG CCCATACATC 
CAGGTGCTGG AGGAGGACTG GCGTCAGGCA CTGCAGGAAC ACCAGGAGCA GGCCAGCACC 
ATCTTCTCCC TACGAAAGGA CCTCCGCCAG GCTGAGGCCC TCCGGACCCG GTGCATGGAG 
GAAAAGGAGA TGTTCGAGCT GCAGTGCCTG GCCTTGCGCA AGGATGCCAA GATGTACAAG 
GACCGGATCG AGGCTATCCT GCAGCAGATG GAGGAAGTCT CCATTGAGCG GGACCAGGCT 
ATGACCTCAA GGGAAGAGCT GCATGCACAG TGTGCCCAAA GCTTTCAGGA CAAAGATAAG 
CTGCGAAAGC AGGTTCGAGA ACTGGATGAG AAGGCCGACG AGTTGCAGCT GCAGCTGTTC 
CAGACCGAGA GCCGATTACT GGCCGCTGAG GGCAGACTCA AGCAGCAGCA ATTGGACATG 
CTCATCCTGA GCTCTGACTT GGAAGACAGT TCCCCCAGGA ACTCCCAGGA GCTTTCACTG 
CCTCAGGACC TGGAGGAGGA TGCCCAGCTC TCAGACAAAG GTGTCCTGGC AGACAGGGAG 
AGCCCAGAGC AGCCCTTCGT GGTTCTGAAC AAGAAGCATC TTTCGCAGAC CCATGACACG 
GTGCCCAGCA GCAGCGAGCC CCCGGAGAAG GAGCGGCGGC GCCTCAAGGA GAGCTTCGAG 
AACTACCGCA GGAAGCGGGC GCTCCGCAAG ATGCAGAACA GCTGGCGACA GGGAGAAGGG 
GATCACGGGA ATACGACAGG CAGCGACAAC ACCGACACCG AGGGCTCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa43566
Clone ID Related Accession (Same CDS sequence) XM_017592019.1
Accession Version XM_017592019.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1359bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product caspase recruitment domain-containing protein 9 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTCAGACT ATGAAAATGA CGACGAGTGC TGGAGTGCCC TGGAGAGCTT CCGGGTGAAG 
CTAATCTCTG TCATTGACCC CTCACGAATC ACACCCTATC TGCGCCAGTG CAAAGTCCTG 
AACCCCGATG ATGAGGAGCA GGTGCTCAGT GACCCCAACC TGGTCATCCG CAAGCGGAAA 
GTGGGTGTGC TCCTGGACAT CCTGCAGCGG ACAGGCCACA AGGGCTACGT GGCCTTTCTT 
GAGAGTCTGG AACTCTACTA CCCTCAGTTA TACAGGAAAG TCACTGGCAA GGAGCCAGCG 
CGTGTCTTCT CCATGATCAT CGACGCATCA GGGGAGTCGG GCCTGACGCA GCTGCTGATG 
ACAGAGGTCA TGAAGCTGCA GAAGAAGGTT CAGGACCTGA CGGCCCTTCT GAGCTCCAAG 
GATGACTTCA TCAAGGAGCT GAGGGTAAAG GACAGCCTCC TGCGCAAGCA CCAGGAGCGG 
GTGCAGCGGC TCAAGGAGGA GTGTGAGCTG AGCAGTGCCG AGCTGAAGCG CTGCAAGGAT 
GAGAACTACG ACCTGGCCAT GCGCCTGGCT CACCTGAGTG AAGAGAAGGG AGCAGCACTC 
ATGCGGAACC GTGACCTGCA GCTTGAGGTG GACCAGCTCA GGCACAGCCT CATGAAGGCA 
GAGGATGACT GCAAGGTGGA GCGCAAACAC ACACTGAAGC TCCGGCACGC CATGGAGCAG 
CGGCCTAGCC AGGAGCTGCT GTGGGACCTG CAGCAGGAGA GGGACTTGTT GCAGGCCCGG 
GTGCAGGAGC TGGAGGTCTC CGTGCAGGAG GGTAAGCTAC ACAGGAATAG CCCATACATC 
CAGGTGCTGG AGGAGGACTG GCGTCAGGCA CTGCAGGAAC ACCAGGAGCA GGCCAGCACC 
ATCTTCTCCC TACGAAAGGA CCTCCGCCAG GCTGAGGCCC TCCGGACCCG GTGCATGGAG 
GAAAAGGAGA TGTTCGAGCT GCAGTGCCTG GCCTTGCGCA AGGATGCCAA GATGTACAAG 
GACCGGATCG AGGCTATCCT GCAGCAGATG GAGGAAGTCT CCATTGAGCG GGACCAGGCT 
ATGACCTCAA GGGAAGAGCT GCATGCACAG TGTGCCCAAA GCTTTCAGGA CAAAGATAAG 
CTGCGAAAGC AGGTTCGAGA ACTGGATGAG AAGGCCGACG AGTTGCAGCT GCAGCTGTTC 
CAGACCGAGA GCCGATTACT GGCCGCTGAG GGCAGACTCA AGCAGCAGCA ATTGGACATG 
CTCATCCTGA GCTCTGACTT GGAAGACAGT TCCCCCAGGA ACTCCCAGGA GGTGTCCTGG 
CAGACAGGGA GAGCCCAGAG CAGCCCTTCG TGGTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017447508.1
CDS230..1588
Translation

Target ORF information:

RefSeq Version XM_017592019.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus caspase recruitment domain family, member 9 (Card9), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017592019.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTCAGACT ATGAAAATGA CGACGAGTGC TGGAGTGCCC TGGAGAGCTT CCGGGTGAAG 
CTAATCTCTG TCATTGACCC CTCACGAATC ACACCCTATC TGCGCCAGTG CAAAGTCCTG 
AACCCCGATG ATGAGGAGCA GGTGCTCAGT GACCCCAACC TGGTCATCCG CAAGCGGAAA 
GTGGGTGTGC TCCTGGACAT CCTGCAGCGG ACAGGCCACA AGGGCTACGT GGCCTTTCTT 
GAGAGTCTGG AACTCTACTA CCCTCAGTTA TACAGGAAAG TCACTGGCAA GGAGCCAGCG 
CGTGTCTTCT CCATGATCAT CGACGCATCA GGGGAGTCGG GCCTGACGCA GCTGCTGATG 
ACAGAGGTCA TGAAGCTGCA GAAGAAGGTT CAGGACCTGA CGGCCCTTCT GAGCTCCAAG 
GATGACTTCA TCAAGGAGCT GAGGGTAAAG GACAGCCTCC TGCGCAAGCA CCAGGAGCGG 
GTGCAGCGGC TCAAGGAGGA GTGTGAGCTG AGCAGTGCCG AGCTGAAGCG CTGCAAGGAT 
GAGAACTACG ACCTGGCCAT GCGCCTGGCT CACCTGAGTG AAGAGAAGGG AGCAGCACTC 
ATGCGGAACC GTGACCTGCA GCTTGAGGTG GACCAGCTCA GGCACAGCCT CATGAAGGCA 
GAGGATGACT GCAAGGTGGA GCGCAAACAC ACACTGAAGC TCCGGCACGC CATGGAGCAG 
CGGCCTAGCC AGGAGCTGCT GTGGGACCTG CAGCAGGAGA GGGACTTGTT GCAGGCCCGG 
GTGCAGGAGC TGGAGGTCTC CGTGCAGGAG GGTAAGCTAC ACAGGAATAG CCCATACATC 
CAGGTGCTGG AGGAGGACTG GCGTCAGGCA CTGCAGGAAC ACCAGGAGCA GGCCAGCACC 
ATCTTCTCCC TACGAAAGGA CCTCCGCCAG GCTGAGGCCC TCCGGACCCG GTGCATGGAG 
GAAAAGGAGA TGTTCGAGCT GCAGTGCCTG GCCTTGCGCA AGGATGCCAA GATGTACAAG 
GACCGGATCG AGGCTATCCT GCAGCAGATG GAGGAAGTCT CCATTGAGCG GGACCAGGCT 
ATGACCTCAA GGGAAGAGCT GCATGCACAG TGTGCCCAAA GCTTTCAGGA CAAAGATAAG 
CTGCGAAAGC AGGTTCGAGA ACTGGATGAG AAGGCCGACG AGTTGCAGCT GCAGCTGTTC 
CAGACCGAGA GCCGATTACT GGCCGCTGAG GGCAGACTCA AGCAGCAGCA ATTGGACATG 
CTCATCCTGA GCTCTGACTT GGAAGACAGT TCCCCCAGGA ACTCCCAGGA GGTGTCCTGG 
CAGACAGGGA GAGCCCAGAG CAGCCCTTCG TGGTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa43567
Clone ID Related Accession (Same CDS sequence) XM_008761626.2
Accession Version XM_008761626.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1296bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product caspase recruitment domain-containing protein 9 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761626.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCAGACT ATGAAAATGA CGACGAGTGC TGGAGTGCCC TGGAGAGCTT CCGGGTGAAG 
CTAATCTCTG TCATTGACCC CTCACGAATC ACACCCTATC TGCGCCAGTG CAAAGTCCTG 
AACCCCGATG ATGAGGAGCA GGTGCTCAGT GACCCCAACC TGGTCATCCG CAAGCGGAAA 
GTGGGTGTGC TCCTGGACAT CCTGCAGCGG ACAGGCCACA AGGGCTACGT GGCCTTTCTT 
GAGAGTCTGG AACTCTACTA CCCTCAGTTA TACAGGAAAG TCACTGGCAA GGAGCCAGCG 
CGTGTCTTCT CCATGATCAT CGACGCATCA GGGGAGTCGG GCCTGACGCA GCTGCTGATG 
ACAGAGGTCA TGAAGCTGCA GAAGAAGGTT CAGGACCTGA CGGCCCTTCT GAGCTCCAAG 
GATGACTTCA TCAAGGAGCT GAGGGTAAAG GACAGCCTCC TGCGCAAGCA CCAGGAGCGG 
GTGCAGCGGC TCAAGGAGGA GTGTGAGCTG AGCAGTGCCG AGCTGAAGCG CTGCAAGGAT 
GAGAACTACG ACCTGGCCAT GCGCCTGGCT CACCTGAGTG AAGAGAAGGG AGCAGCACTC 
ATGCGGAACC GTGACCTGCA GCTTGAGGTG GACCAGCTCA GGCACAGCCT CATGAAGGCA 
GAGGATGACT GCAAGGTGGA GCGCAAACAC ACACTGAAGC TCCGGCACGC CATGGAGCAG 
CGGCCTAGCC AGGAGCTGCT GTGGGACCTG CAGCAGGAGA GGGACTTGTT GCAGGCCCGG 
GTGCAGGAGC TGGAGGTCTC CGTGCAGGAG GGTAAGCTAC ACAGGAATAG CCCATACATC 
CAGGTGCTGG AGGAGGACTG GCGTCAGGCA CTGCAGGAAC ACCAGGAGCA GGCCAGCACC 
ATCTTCTCCC TACGAAAGGA CCTCCGCCAG GCTGAGGCCC TCCGGACCCG GTGCATGGAG 
GAAAAGGAGA TGTTCGAGCT GCAGTGCCTG GCCTTGCGCA AGGATGCCAA GATGTACAAG 
GACCGGATCG AGGCTATCCT GCAGCAGATG GAGGAAGTCT CCATTGAGCG GGACCAGGCT 
ATGACCTCAA GGGAAGAGCT GCATGCACAG TGTGCCCAAA GCTTTCAGGA CAAAGATAAG 
CTGCGAAAGC AGGTTCGAGA ACTGGATGAG AAGGCCGACG AGTTGCAGCT GCAGCTGTTC 
CAGACCGAGA GCCGATTACT GGCCGCTGAG GGCAGACTCA AGCAGCAGCA ATTGGACATG 
CTCATCCTGG TGCTTGGAGC CCCTACCGCC CACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008759848.1
CDS231..1526
Translation

Target ORF information:

RefSeq Version XM_008761626.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus caspase recruitment domain family, member 9 (Card9), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008761626.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCAGACT ATGAAAATGA CGACGAGTGC TGGAGTGCCC TGGAGAGCTT CCGGGTGAAG 
CTAATCTCTG TCATTGACCC CTCACGAATC ACACCCTATC TGCGCCAGTG CAAAGTCCTG 
AACCCCGATG ATGAGGAGCA GGTGCTCAGT GACCCCAACC TGGTCATCCG CAAGCGGAAA 
GTGGGTGTGC TCCTGGACAT CCTGCAGCGG ACAGGCCACA AGGGCTACGT GGCCTTTCTT 
GAGAGTCTGG AACTCTACTA CCCTCAGTTA TACAGGAAAG TCACTGGCAA GGAGCCAGCG 
CGTGTCTTCT CCATGATCAT CGACGCATCA GGGGAGTCGG GCCTGACGCA GCTGCTGATG 
ACAGAGGTCA TGAAGCTGCA GAAGAAGGTT CAGGACCTGA CGGCCCTTCT GAGCTCCAAG 
GATGACTTCA TCAAGGAGCT GAGGGTAAAG GACAGCCTCC TGCGCAAGCA CCAGGAGCGG 
GTGCAGCGGC TCAAGGAGGA GTGTGAGCTG AGCAGTGCCG AGCTGAAGCG CTGCAAGGAT 
GAGAACTACG ACCTGGCCAT GCGCCTGGCT CACCTGAGTG AAGAGAAGGG AGCAGCACTC 
ATGCGGAACC GTGACCTGCA GCTTGAGGTG GACCAGCTCA GGCACAGCCT CATGAAGGCA 
GAGGATGACT GCAAGGTGGA GCGCAAACAC ACACTGAAGC TCCGGCACGC CATGGAGCAG 
CGGCCTAGCC AGGAGCTGCT GTGGGACCTG CAGCAGGAGA GGGACTTGTT GCAGGCCCGG 
GTGCAGGAGC TGGAGGTCTC CGTGCAGGAG GGTAAGCTAC ACAGGAATAG CCCATACATC 
CAGGTGCTGG AGGAGGACTG GCGTCAGGCA CTGCAGGAAC ACCAGGAGCA GGCCAGCACC 
ATCTTCTCCC TACGAAAGGA CCTCCGCCAG GCTGAGGCCC TCCGGACCCG GTGCATGGAG 
GAAAAGGAGA TGTTCGAGCT GCAGTGCCTG GCCTTGCGCA AGGATGCCAA GATGTACAAG 
GACCGGATCG AGGCTATCCT GCAGCAGATG GAGGAAGTCT CCATTGAGCG GGACCAGGCT 
ATGACCTCAA GGGAAGAGCT GCATGCACAG TGTGCCCAAA GCTTTCAGGA CAAAGATAAG 
CTGCGAAAGC AGGTTCGAGA ACTGGATGAG AAGGCCGACG AGTTGCAGCT GCAGCTGTTC 
CAGACCGAGA GCCGATTACT GGCCGCTGAG GGCAGACTCA AGCAGCAGCA ATTGGACATG 
CTCATCCTGG TGCTTGGAGC CCCTACCGCC CACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

CARD9 gene silencing with siRNA protects rats against severe acute pancreatitis: CARD9-dependent NF-?B and P38MAPKs pathway.
Journal of cellular and molecular medicine21(6)1085-1093(2017 Jun)
Yang ZW,Meng XX,Zhang C,Xu P


book

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens.
Nature immunology8(2)198-205(2007 Feb)
Hsu YM,Zhang Y,You Y,Wang D,Li H,Duramad O,Qin XF,Dong C,Lin X


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Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.
Nature442(7103)651-6(2006 Aug)
Gross O,Gewies A,Finger K,Sch?fer M,Sparwasser T,Peschel C,F?rster I,Ruland J


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CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B.
The Journal of biological chemistry275(52)41082-6(2000 Dec)
Bertin J,Guo Y,Wang L,Srinivasula SM,Jacobson MD,Poyet JL,Merriam S,Du MQ,Dyer MJ,Robison KE,DiStefano PS,Alnemri ES