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Entpd2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Entpd2
Entrez Gene ID 64467
Full Name ectonucleoside triphosphate diphosphohydrolase 2
Synonyms Cd39l1,NTPDase2
General protein information
Preferred Names

ectonucleoside triphosphate diphosphohydrolase 2

Names

ectonucleoside triphosphate diphosphohydrolase 2
CD39 antigen-like 1
NTPDase 2
ecto-ATP diphosphohydrolase 2
ecto-ATPDase 2
ecto-ATPase 2
nucleoside triphosphate diphosphohydrolase 2
testicular ecto-ATPase
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3p13
Summary catalyzes the hydrolysis of extracellular nucleotides; may regulate nucleotide mediated signaling [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006233644.3 XP_006233706.1 ectonucleoside triphosphate diphosphohydrolase 2 isoform X2
XM_017592024.1 XP_017447513.1 ectonucleoside triphosphate diphosphohydrolase 2 isoform X3
XM_017592023.1 XP_017447512.1 ectonucleoside triphosphate diphosphohydrolase 2 isoform X1
NM_172030.1 NP_742027.1 ectonucleoside triphosphate diphosphohydrolase 2 precursor

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) ENTPD2 XP_548362.1
Rattus norvegicus (Norway rat) Entpd2 NP_742027.1
Xenopus tropicalis (tropical clawed frog) entpd2 NP_001001252.1
Pan troglodytes (chimpanzee) ENTPD2 XP_001134839.1
ENTPD2 XP_001117802.2
Mus musculus (house mouse) Entpd2 NP_033979.2
Danio rerio (zebrafish) entpd2a.2 XP_687722.1
Gallus gallus (chicken) ENTPD2 NP_990285.1
Danio rerio (zebrafish) entpd2a.1 NP_001004643.1
Danio rerio (zebrafish) entpd2b XP_697600.4
Homo sapiens (human) ENTPD2 NP_982293.1
Bos taurus (cattle) ENTPD2 NP_001099118.1

Gene Ontology


Bibliography

Related articles in PubMed

Extracellular ATP Selectively Upregulates Ecto-Nucleoside Triphosphate Diphosphohydrolase 2 and Ecto-5'-Nucleotidase by Rat Cortical Astrocytes In Vitro.
Brisevac D, Adzic M, Laketa D, Parabucki A, Milosevic M, Lavrnja I, Bjelobaba I, S?vigny J, Kipp M, Nedeljkovic N
Journal of molecular neuroscience : MN57(3)452-62(2015 Nov)

Expression of ecto-nucleoside triphosphate diphosphohydrolase1-3 (NTPDase1-3) by cortical astrocytes after exposure to pro-inflammatory factors in vitro.
Brisevac D, Bajic A, Bjelobaba I, Milosevic M, Stojiljkovic M, Beyer C, Clarner T, Kipp M, Nedeljkovic N
Journal of molecular neuroscience : MN51(3)871-9(2013 Nov)

Crystallographic snapshots along the reaction pathway of nucleoside triphosphate diphosphohydrolases.
Zebisch M, Krauss M, Sch?fer P, Lauble P, Str?ter N
Structure (London, England : 1993)21(8)1460-75(2013 Aug)

Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.
Lu D, Insel PA
The Journal of biological chemistry288(26)19040-9(2013 Jun)

Genetic labeling of Tas1r1 and Tas2r131 taste receptor cells in mice.
Voigt A, H?bner S, Lossow K, Hermans-Borgmeyer I, Boehm U, Meyerhof W
Chemical senses37(9)897-911(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

At the transcriptional level, extracellular ATP upregulated expression of NTPDase1, NTPDase2, NPP2, and eN, while, at translational and functional levels, these were paralleled only by the induction of NTPDase2 and ecto-5'-nucleotidase.
Title: Extracellular ATP Selectively Upregulates Ecto-Nucleoside Triphosphate Diphosphohydrolase 2 and Ecto-5'-Nucleotidase by Rat Cortical Astrocytes In Vitro.

Apo and complex structures of the rat NTPDase2 extracellular domain and Legionella pneumophila NTPDase1.
Title: Crystallographic snapshots along the reaction pathway of nucleoside triphosphate diphosphohydrolases.

two ENTPD isoforms, ENTPD-1 and -2, are expressed in adult rat ventricular CFs
Title: Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.

NTPDase2 overexpression modulates pro-inflammatory cytokine production and platelet reactivity.
Title: Overexpression of NTPDase2 in gliomas promotes systemic inflammation and pulmonary injury.

ATP acts in an autocrine manner to promote its own release and that of dopamine, an action that is controlled by the level of E-NTPDase1/CD39 expression
Title: The expression level of ecto-NTP diphosphohydrolase1/CD39 modulates exocytotic and ischemic release of neurotransmitters in a cellular model of sympathetic neurons.

The following Entpd2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Entpd2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa05986 NM_172030.1
Latest version!		 Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
ORa25479 XM_006233644.3
Latest version!		 Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
ORa60534 XM_017592023.1
Latest version!		 Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 14-16 $307.30
$439.00
ORa60535 XM_017592024.1
Latest version!		 Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 14-16 $307.30
$439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa05986
Clone ID Related Accession (Same CDS sequence) NM_172030.1
Accession Version NM_172030.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1488bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-23
Organism Rattus norvegicus(Norway rat)
Product ectonucleoside triphosphate diphosphohydrolase 2 precursor
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF276940.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF276940.1, BC086558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGACTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAC TTCAGGCCCG AGTGCCAGGA CAAAAGACCC GCCTGGCTGA CTACTGTGCT 
GTAGCCATGT TCATACATCA GCTTCTGAGC CGTGGTTACC ACTTCGATGA GCGCTCCTTC 
AGAGAAGTGG TCTTCCAAAA GAAGGCTGCA GACACGGCTG TCGGCTGGGC GCTGGGCTAC 
ATGCTGAATT TCACTAACCT GATTCCTGCC GACCTCCCCG GACTACGCAA GGGCACCCAC 
TTCAGCTCCT GGGTCGCTCT CCTGCTGCTC TTCACAGTCC TGATCTTGGC GGCGCTGGTC 
CTGCTCCTGC GCCAGGTGCG TTCTGCCAAG TCTCCAGGCG CCCTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_742027.1
CDS2..1489
Translation

Target ORF information:

RefSeq Version NM_172030.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_172030.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGACTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAC TTCAGGCCCG AGTGCCAGGA CAAAAGACCC GCCTGGCTGA CTACTGTGCT 
GTAGCCATGT TCATACATCA GCTTCTGAGC CGTGGTTACC ACTTCGATGA GCGCTCCTTC 
AGAGAAGTGG TCTTCCAAAA GAAGGCTGCA GACACGGCTG TCGGCTGGGC GCTGGGCTAC 
ATGCTGAATT TCACTAACCT GATTCCTGCC GACCTCCCCG GACTACGCAA GGGCACCCAC 
TTCAGCTCCT GGGTCGCTCT CCTGCTGCTC TTCACAGTCC TGATCTTGGC GGCGCTGGTC 
CTGCTCCTGC GCCAGGTGCG TTCTGCCAAG TCTCCAGGCG CCCTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa25479
Clone ID Related Accession (Same CDS sequence) XM_006233644.3
Accession Version XM_006233644.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1638bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product ectonucleoside triphosphate diphosphohydrolase 2 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233644.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGGCTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAC TTCAGGCCCG AGTGCCAGGA CAAAAGACCC GCCTGGCTGA CTACTGTGCT 
GTAGCCATGT TCATACATCA GCTTCTGAGC CGTGGTTACC ACTTCGATGA GCGCTCCTTC 
AGAGAAGTGG TCTTCCAAAA GAAGGCTGCA GACACGGCTG TCGGCTGGGC GCTGGGCTAC 
ATGCTGAATT TGACTAACCT GATTCCTGCC GACCTCCCCG GACTACGCAA GGGCACCCAC 
TTCAGCTCCT GGGTCGCTCT CCTGCTGCTC TTCACAGTCC TGATCTTGGC GGCGCTGGTC 
CTGCTCCTGC GCCAGGATGT CAGGTCTCAG CCTGTGACTC AGGGTGAGGT CCATTCGGAG 
TGGGACTTTT GTTCTGATCT TCAGGGCCCT GGGAACTTTC TGTCTGGGCC TTTAGAAAGG 
CAGGCACCAG AGCCTACAGG CTGGGAGTCA GTTCCATGCC TACTTGTAAA AACTTTTGTA 
ATAAAAGATT TTTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233706.1
CDS101..1738
Translation

Target ORF information:

RefSeq Version XM_006233644.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233644.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGGCTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAC TTCAGGCCCG AGTGCCAGGA CAAAAGACCC GCCTGGCTGA CTACTGTGCT 
GTAGCCATGT TCATACATCA GCTTCTGAGC CGTGGTTACC ACTTCGATGA GCGCTCCTTC 
AGAGAAGTGG TCTTCCAAAA GAAGGCTGCA GACACGGCTG TCGGCTGGGC GCTGGGCTAC 
ATGCTGAATT TGACTAACCT GATTCCTGCC GACCTCCCCG GACTACGCAA GGGCACCCAC 
TTCAGCTCCT GGGTCGCTCT CCTGCTGCTC TTCACAGTCC TGATCTTGGC GGCGCTGGTC 
CTGCTCCTGC GCCAGGATGT CAGGTCTCAG CCTGTGACTC AGGGTGAGGT CCATTCGGAG 
TGGGACTTTT GTTCTGATCT TCAGGGCCCT GGGAACTTTC TGTCTGGGCC TTTAGAAAGG 
CAGGCACCAG AGCCTACAGG CTGGGAGTCA GTTCCATGCC TACTTGTAAA AACTTTTGTA 
ATAAAAGATT TTTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa60534
Clone ID Related Accession (Same CDS sequence) XM_017592023.1
Accession Version XM_017592023.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1707bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product ectonucleoside triphosphate diphosphohydrolase 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGGCTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAT GGCCATCTTT GCTGTCCTCT CCATCCAGCT GTTGGAAGGG GAGAACACAA 
GGTTCCAGCA GTCACGAGCT TCAGGCCCGA GTGCCAGGAC AAAAGACCCG CCTGGCTGAC 
TACTGTGCTG TAGCCATGTT CATACATCAG CTTCTGAGCC GTGGTTACCA CTTCGATGAG 
CGCTCCTTCA GAGAAGTGGT CTTCCAAAAG AAGGCTGCAG ACACGGCTGT CGGCTGGGCG 
CTGGGCTACA TGCTGAATTT GACTAACCTG ATTCCTGCCG ACCTCCCCGG ACTACGCAAG 
GGCACCCACT TCAGCTCCTG GGTCGCTCTC CTGCTGCTCT TCACAGTCCT GATCTTGGCG 
GCGCTGGTCC TGCTCCTGCG CCAGGATGTC AGGTCTCAGC CTGTGACTCA GGGTGAGGTC 
CATTCGGAGT GGGACTTTTG TTCTGATCTT CAGGGCCCTG GGAACTTTCT GTCTGGGCCT 
TTAGAAAGGC AGGCACCAGA GCCTACAGGC TGGGAGTCAG TTCCATGCCT ACTTGTAAAA 
ACTTTTGTAA TAAAAGATTT TTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017447512.1
CDS102..1808
Translation

Target ORF information:

RefSeq Version XM_017592023.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017592023.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGGCTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAT GGCCATCTTT GCTGTCCTCT CCATCCAGCT GTTGGAAGGG GAGAACACAA 
GGTTCCAGCA GTCACGAGCT TCAGGCCCGA GTGCCAGGAC AAAAGACCCG CCTGGCTGAC 
TACTGTGCTG TAGCCATGTT CATACATCAG CTTCTGAGCC GTGGTTACCA CTTCGATGAG 
CGCTCCTTCA GAGAAGTGGT CTTCCAAAAG AAGGCTGCAG ACACGGCTGT CGGCTGGGCG 
CTGGGCTACA TGCTGAATTT GACTAACCTG ATTCCTGCCG ACCTCCCCGG ACTACGCAAG 
GGCACCCACT TCAGCTCCTG GGTCGCTCTC CTGCTGCTCT TCACAGTCCT GATCTTGGCG 
GCGCTGGTCC TGCTCCTGCG CCAGGATGTC AGGTCTCAGC CTGTGACTCA GGGTGAGGTC 
CATTCGGAGT GGGACTTTTG TTCTGATCTT CAGGGCCCTG GGAACTTTCT GTCTGGGCCT 
TTAGAAAGGC AGGCACCAGA GCCTACAGGC TGGGAGTCAG TTCCATGCCT ACTTGTAAAA 
ACTTTTGTAA TAAAAGATTT TTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa60535
Clone ID Related Accession (Same CDS sequence) XM_017592024.1
Accession Version XM_017592024.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1557bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product ectonucleoside triphosphate diphosphohydrolase 2 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGGCTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAT GGCCATCTTT GCTGTCCTCT CCATCCAGCT GTTGGAAGGG GAGAACACAA 
GGTTCCAGCA GTCACGAGCT TCAGGCCCGA GTGCCAGGAC AAAAGACCCG CCTGGCTGAC 
TACTGTGCTG TAGCCATGTT CATACATCAG CTTCTGAGCC GTGGTTACCA CTTCGATGAG 
CGCTCCTTCA GAGAAGTGGT CTTCCAAAAG AAGGCTGCAG ACACGGCTGT CGGCTGGGCG 
CTGGGCTACA TGCTGAATTT GACTAACCTG ATTCCTGCCG ACCTCCCCGG ACTACGCAAG 
GGCACCCACT TCAGCTCCTG GGTCGCTCTC CTGCTGCTCT TCACAGTCCT GATCTTGGCG 
GCGCTGGTCC TGCTCCTGCG CCAGGTGCGT TCTGCCAAGT CTCCAGGCGC CCTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017447513.1
CDS101..1657
Translation

Target ORF information:

RefSeq Version XM_017592024.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017592024.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGCTGGAA AGTTGGTGTC ACTGGTGCCA CCCCTGCTGC TGGCTGCCGC GGGCCTCGCC 
GGCCTTCTGC TACTTTGCGT CCCTACCCAA GACGTCCGGG AGCCGCCCGC CCTCAAGTAC 
GGCATTGTCC TGGATGCGGG CTCTTCACAC ACATCCATGT TTGTCTACAA GTGGCCAGCG 
GACAAGGAGA ATGACACAGG CATCGTGGGC CAGCACAGCT CTTGTGATGT TCAAGGTGGT 
GGCATCTCCA GCTATGCAAA TGACCCCTCT AAGGCAGGCC AGAGTCTGGT CCGATGCCTT 
GAGCAGGCCC TTCGGGATGT ACCCAGAGAC AGACATGCTA GCACACCACT CTACCTGGGA 
GCTACAGCAG GCATGCGCCT GCTCAACCTG ACCAGCCCAG AGGCCACAGC CAGGGTGCTT 
GAGGCAGTGA CACAGACGCT CACACAGTAC CCCTTTGACT TCCGTGGTGC TCGCATCCTC 
TCGGGACAGG ATGAAGGGGT GTTTGGCTGG GTGACTGCCA ACTACCTGCT GGAGAACTTC 
ATCAAGTATG GCTGGGTGGG CCGGTGGATA CGGCCAAGGA AGGGAACACT GGGGGCCATG 
GACCTTGGGG GTGCTTCGAC ACAGATCACC TTTGAGACAA CCAGTCCCTC TGAAGATCCA 
GGCAACGAGG TTCATTTGCG ACTCTATGGC CAGCATTACC GCGTTTACAC ACATAGCTTC 
CTCTGCTATG GCCGAGACCA GATTCTCCTG AGGCTTCTGG CCAGTGCCCT CCAGATCCAT 
CGCTTCCACC CCTGCTGGCC AAAGGGCTAC TCTACCCAAG TGCTGCTCCA GGAAGTCTAC 
CAGTCGCCAT GCACGATGGG TCAGCGTCCC CGGGCCTTCA ATGGCAGTGC CATCGTCAGC 
CTGTCAGGAA CCAGCAATGC TACCCTGTGT CGTGACCTCG TCTCTCGGCT CTTCAACATC 
TCCTCCTGCC CCTTTTCCCA ATGCTCCTTC AATGGGGTCT TCCAGCCTCC CGTGGCTGGA 
AACTTCATAG CCTTTTCTGC TTTCTACTAT ACTGTGGACT TCCTGACAAC AGTGATGGGG 
CTGCCTGTGG GAACCCTGAA GCAGCTGGAG GAAGCCACAG AGATCACCTG CAACCAGACA 
TGGACTGAAT GGCCATCTTT GCTGTCCTCT CCATCCAGCT GTTGGAAGGG GAGAACACAA 
GGTTCCAGCA GTCACGAGCT TCAGGCCCGA GTGCCAGGAC AAAAGACCCG CCTGGCTGAC 
TACTGTGCTG TAGCCATGTT CATACATCAG CTTCTGAGCC GTGGTTACCA CTTCGATGAG 
CGCTCCTTCA GAGAAGTGGT CTTCCAAAAG AAGGCTGCAG ACACGGCTGT CGGCTGGGCG 
CTGGGCTACA TGCTGAATTT GACTAACCTG ATTCCTGCCG ACCTCCCCGG ACTACGCAAG 
GGCACCCACT TCAGCTCCTG GGTCGCTCTC CTGCTGCTCT TCACAGTCCT GATCTTGGCG 
GCGCTGGTCC TGCTCCTGCG CCAGGTGCGT TCTGCCAAGT CTCCAGGCGC CCTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Extracellular ATP Selectively Upregulates Ecto-Nucleoside Triphosphate Diphosphohydrolase 2 and Ecto-5'-Nucleotidase by Rat Cortical Astrocytes In Vitro.
Journal of molecular neuroscience : MN57(3)452-62(2015 Nov)
Brisevac D,Adzic M,Laketa D,Parabucki A,Milosevic M,Lavrnja I,Bjelobaba I,S?vigny J,Kipp M,Nedeljkovic N


book

Expression of ecto-nucleoside triphosphate diphosphohydrolase1-3 (NTPDase1-3) by cortical astrocytes after exposure to pro-inflammatory factors in vitro.
Journal of molecular neuroscience : MN51(3)871-9(2013 Nov)
Brisevac D,Bajic A,Bjelobaba I,Milosevic M,Stojiljkovic M,Beyer C,Clarner T,Kipp M,Nedeljkovic N


book

Crystallographic snapshots along the reaction pathway of nucleoside triphosphate diphosphohydrolases.
Structure (London, England : 1993)21(8)1460-75(2013 Aug)
Zebisch M,Krauss M,Sch?fer P,Lauble P,Str?ter N


book

Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.
The Journal of biological chemistry288(26)19040-9(2013 Jun)
Lu D,Insel PA


book

Genetic labeling of Tas1r1 and Tas2r131 taste receptor cells in mice.
Chemical senses37(9)897-911(2012 Nov)
Voigt A,H?bner S,Lossow K,Hermans-Borgmeyer I,Boehm U,Meyerhof W