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Scamp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Scamp2
Entrez Gene ID 65168
Full Name secretory carrier membrane protein 2
General protein information
Preferred Names

secretory carrier membrane protein 2

Names

secretory carrier-associated membrane protein 2
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

8

8q24
Summary may be involved in membrane trafficking and endocytosis [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_023955.1 NP_076445.1 secretory carrier-associated membrane protein 2
XM_017595894.1 XP_017451383.1 secretory carrier-associated membrane protein 2 isoform X1

Pathways from BioSystems


Homologies


Gallus gallus (chicken) SCAMP2 XP_001233172.2
Arabidopsis thaliana (thale cress) AT2G20840 NP_179680.1
Pan troglodytes (chimpanzee) SCAMP2 XP_001135846.2
Arabidopsis thaliana (thale cress) AT1G03550 NP_563686.1
Oryza sativa (rice) Os01g0780500 NP_001044437.1
Mus musculus (house mouse) Scamp2 NP_073724.1
Rattus norvegicus (Norway rat) Scamp2 NP_076445.1
Oryza sativa (rice) Os07g0564600 NP_001060004.1
Homo sapiens (human) SCAMP2 NP_005688.2
Canis lupus familiaris (dog) SCAMP2 XP_544777.2
Bos taurus (cattle) SCAMP2 NP_001095640.1
Danio rerio (zebrafish) scamp2l NP_957488.1
Arabidopsis thaliana (thale cress) AT1G11180 NP_001184960.1
SCAMP2 XP_001098273.2
Danio rerio (zebrafish) scamp2 NP_998543.1
Arabidopsis thaliana (thale cress) SC3 NP_176320.1
Oryza sativa (rice) Os05g0503000 NP_001055977.1
Xenopus tropicalis (tropical clawed frog) scamp2 NP_001001223.1

Gene Ontology


Bibliography

Related articles in PubMed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis.
Liao H, Zhang J, Shestopal S, Szabo G, Castle A, Castle D
American journal of physiology. Cell physiology294(3)C797-809(2008 Mar)

Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.
M?ller HK, Wiborg O, Haase J
The Journal of biological chemistry281(39)28901-9(2006 Sep)

SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells.
Liu L, Liao H, Castle A, Zhang J, Casanova J, Szabo G, Castle D
Molecular biology of the cell16(10)4463-72(2005 Oct)

Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.
Lin PJ, Williams WP, Luu Y, Molday RS, Orlowski J, Numata M
Journal of cell science118(Pt 9)1885-97(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SCAMP isoforms regulate membrane fusion and dense core vesicle exocytosis in neurons.
Title: Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis.

SCAMP2 plays an important role in the regulation of the subcellular distribution of SERT
Title: Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.

SCAMP2 couples Arf6-stimulated PLD activity to exocytosis and links this process to formation of fusion pores.
Title: SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells.

SCAMP2 not only colocalizes with fusion sites but also appears to have an essential function in granule exocytosis through actions mediated by its E peptide-containing domain
Title: Role of secretory carrier membrane protein SCAMP2 in granule exocytosis.

role in perturbation of a very late step of regulated exocytosis
Title: Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide.

The following Scamp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scamp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa06631 NM_023955.1
Latest version!		 Rattus norvegicus secretory carrier membrane protein 2 (Scamp2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
ORa62541 XM_017595894.1
Latest version!		 Rattus norvegicus secretory carrier membrane protein 2 (Scamp2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa06631
Clone ID Related Accession (Same CDS sequence) NM_023955.1
Accession Version NM_023955.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 990bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-05-26
Organism Rattus norvegicus(Norway rat)
Product secretory carrier-associated membrane protein 2
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085862.1. On Nov 22, 2004 this sequence version replaced XM_343399.1. ##Evidence-Data-START## Transcript exon combination :: BC085862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCGGCCT TCGACACTAA CCCCTTCGCG GACCCAGTGG ATGTAAACCC CTTCCAGGAT 
CCTTCTGTGA CCCAGCTGAC CAGTGCTCCT CAGAGTGGCC TGGCTGAGTT CAATCCCTTC 
TCAGAGACAA ATGCAGCGAC AACAGTTCCT GTCACACAAC TTCCTGGGCC CTCCCAGCCA 
GCAGTTCTCC AGCCCTCAGT GGAGCCAGCA CAGCCATCGC CCCAGGCTGT TGCGGCTGCA 
GCCCAGGCAG GCCTGCTTCG GCAGCAGGAA GAGTTAGACA GGAAAGCTGC TGAGCTGGAA 
CGCAAGGAGC GAGAGTTGCA GAACACTGCG GCGAATTTGC ATGTAAGAGA AAACAACTGG 
CCGCCACTCC CCTCATGGTG CCCTGTGAAA CCCTGCTTCT ATCAGGACTT CTCCACGGAG 
ATCCCTGCCG ACTACCAGCG GATATGCAAG ATGCTTTACT ATCTGTGGAT GTTGCATTCA 
GTGACTCTGT TTCTAAACCT GCTTGCATGC CTGGCCTGGT TCACAAGTGA CGCAGCTAAT 
GGAACAGCCT TTGGCCTCTC CATCCTTTGG TTTCTGATTT TCACGCCCTG TGCCTTCCTT 
TGTTGGTACC GACCCATCTA CAAGGCTTTC AGGTCTGACA ACTCTTTCAG CTTCTTCGTG 
TTCTTTTTTG TATTTTTTTG TCAAATAGGA ATCTACTTCA TCCAGTTGAT TGGCTTGCCT 
AACTTGGGGA CCAGTGGTTG GCTCGCAGCC CTCTCTACAG TGAATAAGGG GCCCTTAGCT 
GTGACCATCA TCATGATGGT AGTGGCTGGC TTCTTTACCC TCTGTGCTGG GCTCTCACTC 
TTCCTCCTGC AGCGGGTCCA TGCCTTCTAC CGCCGAACAG GAGCCAGCTT CCAGCAGGCT 
CAGGAAGAAT TCTCCCAGGG CATCTTCAGC AGCAGAACCT TCCGCACTGC TGCCTCGTCT 
GCTGCCCGAG GAACCTTCCA GGGGAATTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_076445.1
CDS97..1086
Translation

Target ORF information:

RefSeq Version NM_023955.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus secretory carrier membrane protein 2 (Scamp2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_023955.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCGGCCT TCGACACTAA CCCCTTCGCG GACCCAGTGG ATGTAAACCC CTTCCAGGAT 
CCTTCTGTGA CCCAGCTGAC CAGTGCTCCT CAGAGTGGCC TGGCTGAGTT CAATCCCTTC 
TCAGAGACAA ATGCAGCGAC AACAGTTCCT GTCACACAAC TTCCTGGGCC CTCCCAGCCA 
GCAGTTCTCC AGCCCTCAGT GGAGCCAGCA CAGCCATCGC CCCAGGCTGT TGCGGCTGCA 
GCCCAGGCAG GCCTGCTTCG GCAGCAGGAA GAGTTAGACA GGAAAGCTGC TGAGCTGGAA 
CGCAAGGAGC GAGAGTTGCA GAACACTGCG GCGAATTTGC ATGTAAGAGA AAACAACTGG 
CCGCCACTCC CCTCATGGTG CCCTGTGAAA CCCTGCTTCT ATCAGGACTT CTCCACGGAG 
ATCCCTGCCG ACTACCAGCG GATATGCAAG ATGCTTTACT ATCTGTGGAT GTTGCATTCA 
GTGACTCTGT TTCTAAACCT GCTTGCATGC CTGGCCTGGT TCACAAGTGA CGCAGCTAAT 
GGAACAGCCT TTGGCCTCTC CATCCTTTGG TTTCTGATTT TCACGCCCTG TGCCTTCCTT 
TGTTGGTACC GACCCATCTA CAAGGCTTTC AGGTCTGACA ACTCTTTCAG CTTCTTCGTG 
TTCTTTTTTG TATTTTTTTG TCAAATAGGA ATCTACTTCA TCCAGTTGAT TGGCTTGCCT 
AACTTGGGGA CCAGTGGTTG GCTCGCAGCC CTCTCTACAG TGAATAAGGG GCCCTTAGCT 
GTGACCATCA TCATGATGGT AGTGGCTGGC TTCTTTACCC TCTGTGCTGG GCTCTCACTC 
TTCCTCCTGC AGCGGGTCCA TGCCTTCTAC CGCCGAACAG GAGCCAGCTT CCAGCAGGCT 
CAGGAAGAAT TCTCCCAGGG CATCTTCAGC AGCAGAACCT TCCGCACTGC TGCCTCGTCT 
GCTGCCCGAG GAACCTTCCA GGGGAATTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa62541
Clone ID Related Accession (Same CDS sequence) XM_017595894.1
Accession Version XM_017595894.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product secretory carrier-associated membrane protein 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGTCGGCCT TCGACACTAA CCCCTTCGCG GACCCAGTGG ATGTAAACCC CTTCCAGGAT 
CCTTCTGTGA CCCAGCTGAC CAGTGCTCCT CAGAGTGGCC TGGCTGAGTT CAATCCCTTC 
TCAGAGACAA ATGCAGCGAC AACAGTTCCT GTCACACAAC TTCCTGGGCC CTCCCAGCCA 
GCAGTTCTCC AGCCCTCAGT GGAGCCAGCA CAGCCATCGC CCCAGCTCCT GCTTAGACAG 
GCCAGCAAGT TTCTGCCTGC CCGATTCCTG GCAGCGGGTG AGCCCTCAGA GAGGCAGATG 
CTACTAGGAG GAGATAGTAG TCCCAGGGAC AGCTACATGT GCAAGCTTCC GAAGGCTGTT 
GCGGCTGCAG CCCAGGCAGG CCTGCTTCGG CAGCAGGAAG AGTTAGACAG GAAAGCTGCT 
GAGCTGGAAC GCAAGGAGCG AGAGTTGCAG AACACTGCGG CGAATTTGCA TGTAAGAGAA 
AACAACTGGC CGCCACTCCC CTCATGGTGC CCTGTGAAAC CCTGCTTCTA TCAGGACTTC 
TCCACGGAGA TCCCTGCCGA CTACCAGCGG ATATGCAAGA TGCTTTACTA TCTGTGGATG 
TTGCATTCAG TGACTCTGTT TCTAAACCTG CTTGCATGCC TGGCCTGGTT CACAAGTGAC 
GCAGCTAATG GAACAGCCTT TGGCCTCTCC ATCCTTTGGT TTCTGATTTT CACGCCCTGT 
GCCTTCCTTT GTTGGTACCG ACCCATCTAC AAGGCTTTCA GGTCTGACAA CTCTTTCAGC 
TTCTTCGTGT TCTTTTTTGT ATTTTTTTGT CAAATAGGAA TCTACTTCAT CCAGTTGATT 
GGCTTGCCTA ACTTGGGGAC CAGTGGTTGG CTCGCAGCCC TCTCTACAGT GAATAAGGGG 
CCCTTAGCTG TGACCATCAT CATGATGGTA GTGGCTGGCT TCTTTACCCT CTGTGCTGGG 
CTCTCACTCT TCCTCCTGCA GCGGGTCCAT GCCTTCTACC GCCGAACAGG AGCCAGCTTC 
CAGCAGGCTC AGGAAGAATT CTCCCAGGGC ATCTTCAGCA GCAGAACCTT CCGCACTGCT 
GCCTCGTCTG CTGCCCGAGG AACCTTCCAG GGGAATTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017451383.1
CDS126..1244
Translation

Target ORF information:

RefSeq Version XM_017595894.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus secretory carrier membrane protein 2 (Scamp2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017595894.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGTCGGCCT TCGACACTAA CCCCTTCGCG GACCCAGTGG ATGTAAACCC CTTCCAGGAT 
CCTTCTGTGA CCCAGCTGAC CAGTGCTCCT CAGAGTGGCC TGGCTGAGTT CAATCCCTTC 
TCAGAGACAA ATGCAGCGAC AACAGTTCCT GTCACACAAC TTCCTGGGCC CTCCCAGCCA 
GCAGTTCTCC AGCCCTCAGT GGAGCCAGCA CAGCCATCGC CCCAGCTCCT GCTTAGACAG 
GCCAGCAAGT TTCTGCCTGC CCGATTCCTG GCAGCGGGTG AGCCCTCAGA GAGGCAGATG 
CTACTAGGAG GAGATAGTAG TCCCAGGGAC AGCTACATGT GCAAGCTTCC GAAGGCTGTT 
GCGGCTGCAG CCCAGGCAGG CCTGCTTCGG CAGCAGGAAG AGTTAGACAG GAAAGCTGCT 
GAGCTGGAAC GCAAGGAGCG AGAGTTGCAG AACACTGCGG CGAATTTGCA TGTAAGAGAA 
AACAACTGGC CGCCACTCCC CTCATGGTGC CCTGTGAAAC CCTGCTTCTA TCAGGACTTC 
TCCACGGAGA TCCCTGCCGA CTACCAGCGG ATATGCAAGA TGCTTTACTA TCTGTGGATG 
TTGCATTCAG TGACTCTGTT TCTAAACCTG CTTGCATGCC TGGCCTGGTT CACAAGTGAC 
GCAGCTAATG GAACAGCCTT TGGCCTCTCC ATCCTTTGGT TTCTGATTTT CACGCCCTGT 
GCCTTCCTTT GTTGGTACCG ACCCATCTAC AAGGCTTTCA GGTCTGACAA CTCTTTCAGC 
TTCTTCGTGT TCTTTTTTGT ATTTTTTTGT CAAATAGGAA TCTACTTCAT CCAGTTGATT 
GGCTTGCCTA ACTTGGGGAC CAGTGGTTGG CTCGCAGCCC TCTCTACAGT GAATAAGGGG 
CCCTTAGCTG TGACCATCAT CATGATGGTA GTGGCTGGCT TCTTTACCCT CTGTGCTGGG 
CTCTCACTCT TCCTCCTGCA GCGGGTCCAT GCCTTCTACC GCCGAACAGG AGCCAGCTTC 
CAGCAGGCTC AGGAAGAATT CTCCCAGGGC ATCTTCAGCA GCAGAACCTT CCGCACTGCT 
GCCTCGTCTG CTGCCCGAGG AACCTTCCAG GGGAATTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W


book

Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis.
American journal of physiology. Cell physiology294(3)C797-809(2008 Mar)
Liao H,Zhang J,Shestopal S,Szabo G,Castle A,Castle D


book

Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.
The Journal of biological chemistry281(39)28901-9(2006 Sep)
M?ller HK,Wiborg O,Haase J


book

SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells.
Molecular biology of the cell16(10)4463-72(2005 Oct)
Liu L,Liao H,Castle A,Zhang J,Casanova J,Szabo G,Castle D


book

Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.
Journal of cell science118(Pt 9)1885-97(2005 May)
Lin PJ,Williams WP,Luu Y,Molday RS,Orlowski J,Numata M