Gene Symbol | Myl4 |
Entrez Gene ID | 688228 |
Full Name | myosin, light chain 4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Myl4 cDNA ORF clone
Gene Symbol | Myl4 |
Entrez Gene ID | 688228 |
Full Name | myosin, light chain 4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001109495.1 | NP_001102965.1 | myosin light chain 4 |
Rattus norvegicus (Norway rat) | Myl4 | NP_001102965.1 |
Gallus gallus (chicken) | MYL4 | XP_003642828.1 |
Danio rerio (zebrafish) | myl4 | NP_001020354.1 |
LOC717354 | XP_001116001.1 | |
Mus musculus (house mouse) | Myl4 | NP_034988.2 |
Homo sapiens (human) | MYL4 | NP_002467.1 |
Canis lupus familiaris (dog) | MYL4 | XP_005624249.1 |
Xenopus tropicalis (tropical clawed frog) | myl4 | NP_001096232.1 |
Pan troglodytes (chimpanzee) | MYL4 | XP_511623.1 |
Bos taurus (cattle) | MYL4 | NP_001068617.1 |
Dysfunction of Myosin Light-Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically-Engineered Rats.
Peng W, Li M, Li H, Tang K, Zhuang J, Zhang J, Xiao J, Jiang H, Li D, Yu Y, Sham PC, Nattel S, Xu Y
Journal of the American Heart Association6(11)(2017 Oct)
Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.
Haase H, Dobbernack G, T?nnemann G, Karczewski P, Cardoso C, Petzhold D, Schlegel WP, Lutter S, Pierschalek P, Behlke J, Morano I
FASEB journal : official publication of the Federation of American Societies for Experimental Biology20(7)865-73(2006 May)
Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model.
Abdelaziz AI, Segaric J, Bartsch H, Petzhold D, Schlegel WP, Kott M, Seefeldt I, Klose J, Bader M, Haase H, Morano I
Journal of molecular medicine (Berlin, Germany)82(4)265-74(2004 Apr)
The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function.
Timson DJ, Trayer HR, Trayer IP
European journal of biochemistry255(3)654-62(1998 Aug)
Different actin affinities of human cardiac essential myosin light chain isoforms.
Morano I, Haase H
FEBS letters408(1)71-4(1997 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Myl4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myl4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10105 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109495.1 | |
Accession Version | NM_001109495.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | myosin light chain 4 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On Oct 4, 2007 this sequence version replaced XM_001081553.1. ##Evidence-Data-START## CDS exon combination :: FN805610.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTCCCA AGAAGCCTGA GCCCAAGAAG GAGACTGCCA AGGCAGCCGC AGCCCCTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102965.1 |
CDS | 71..652 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001109495.1 |
1 | ATGCCTCCCA AGAAGCCTGA GCCCAAGAAG GAGACTGCCA AGGCAGCCGC AGCCCCTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dysfunction of Myosin Light-Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically-Engineered Rats. |
Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats. |
Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model. |
The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function. |
Different actin affinities of human cardiac essential myosin light chain isoforms. |