Gene Symbol | Upk2 |
Entrez Gene ID | 689093 |
Full Name | uroplakin 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Upk2 cDNA ORF clone
Gene Symbol | Upk2 |
Entrez Gene ID | 689093 |
Full Name | uroplakin 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001109523.1 | NP_001102993.1 | uroplakin-2 precursor |
MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells.
Zhou G, Liang FX, Romih R, Wang Z, Liao Y, Ghiso J, Luque-Garcia JL, Neubert TA, Kreibich G, Alonso MA, Schaeren-Wiemers N, Sun TT
Molecular biology of the cell23(7)1354-66(2012 Apr)
Altered expression of UPIa, UPIb, UPII, and UPIIIa during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats.
Zupan?i? D, Ov?ak Z, Vidmar G, Romih R
Virchows Archiv : an international journal of pathology458(5)603-13(2011 May)
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Immunohistochemical analysis of uroplakins, urothelial specific proteins, in ovarian Brenner tumors, normal tissues, and benign and neoplastic lesions of the female genital tract.
Ogawa K, Johansson SL, Cohen SM
The American journal of pathology155(4)1047-50(1999 Oct)
Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins.
Wu XR, Lin JH, Walz T, H?ner M, Yu J, Aebi U, Sun TT
The Journal of biological chemistry269(18)13716-24(1994 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
During urothelial carcinogenesis, UPII expression was the most decreased in all urothelial lesions, while UPIa, UPIb, and UPIIIa expression was differently altered in different types of lesions
Title: Altered expression of UPIa, UPIb, UPII, and UPIIIa during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats.
The following Upk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Upk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10205 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109523.1 | |
Accession Version | NM_001109523.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | uroplakin-2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473975.1. On Oct 4, 2007 this sequence version replaced XM_001060120.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052297, SAMEA2689595 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCATCCA CACTGCCTGT CCAGACCTTG CGCCTGTTTC TGATTTTGCT GGCTGTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102993.1 |
CDS | 61..615 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001109523.1 |
1 | ATGGCATCCA CACTGCCTGT CCAGACCTTG CGCCTGTTTC TGATTTTGCT GGCTGTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells. |
Altered expression of UPIa, UPIb, UPII, and UPIIIa during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats. |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
Immunohistochemical analysis of uroplakins, urothelial specific proteins, in ovarian Brenner tumors, normal tissues, and benign and neoplastic lesions of the female genital tract. |
Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins. |