Gene Symbol | Alcam |
Entrez Gene ID | 79559 |
Full Name | activated leukocyte cell adhesion molecule |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Alcam cDNA ORF clone
Gene Symbol | Alcam |
Entrez Gene ID | 79559 |
Full Name | activated leukocyte cell adhesion molecule |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017598076.1 | XP_017453565.1 | CD166 antigen isoform X1 |
XM_017598077.1 | XP_017453566.1 | CD166 antigen isoform X2 |
NM_031753.1 | NP_113941.1 | CD166 antigen precursor |
Danio rerio (zebrafish) | alcama | NP_571075.1 |
Homo sapiens (human) | ALCAM | NP_001618.2 |
Pan troglodytes (chimpanzee) | ALCAM | XP_516634.2 |
Canis lupus familiaris (dog) | ALCAM | XP_005639492.1 |
ALCAM | XP_001099834.1 | |
Gallus gallus (chicken) | ALCAM | NP_990510.1 |
Danio rerio (zebrafish) | alcamb | NP_997799.3 |
Bos taurus (cattle) | ALCAM | NP_776663.1 |
Mus musculus (house mouse) | Alcam | NP_033785.1 |
Rattus norvegicus (Norway rat) | Alcam | NP_113941.1 |
Xenopus tropicalis (tropical clawed frog) | alcam | NP_001072753.1 |
Activated leukocyte cell adhesion molecule is involved in excitatory synaptic transmission and plasticity in the rat spinal dorsal horn.
Park ES, Jeon SM, Weon H, Cho HJ, Youn DH
Neuroscience letters6569-14(2017 Aug)
Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction.
Chappell PE, Garner LI, Yan J, Metcalfe C, Hatherley D, Johnson S, Robinson CV, Lea SM, Brown MH
Structure (London, England : 1993)23(8)1426-36(2015 Aug)
Activated leukocyte cell adhesion molecule modulates neurotrophin signaling.
Wade A, Thomas C, Kalmar B, Terenzio M, Garin J, Greensmith L, Schiavo G
Journal of neurochemistry121(4)575-86(2012 May)
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ALCAM synergizes with nerve growth factor to induce neuronal differentiation, raising the possibility that it functions not only as an adhesion molecule but also in the modulation of growth factor signaling in the nervous system
Title: Activated leukocyte cell adhesion molecule modulates neurotrophin signaling.
The immunolocalisation of the stem cell-specific markers Notch-1, Delta, CD105 and CD166 was studied in rat femoral head articular cartilage. Corticosteroid (methylprednisolone) treatment was found to decrease the activity of these markers.
Title: The effect of systemic corticosteroid treatment on the immunolocalisation of Notch-1, Delta, CD105 and CD166 in rat articular cartilage.
Localization of ALCAM specifically at cell-cell junctions in endothelial cells supported its role in transendothelial migration
Title: Activated leukocyte cell adhesion molecule is a component of the endothelial junction involved in transendothelial monocyte migration.
The following Alcam gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Alcam cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa08655 | |
Clone ID Related Accession (Same CDS sequence) | NM_031753.1 | |
Accession Version | NM_031753.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1752bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | CD166 antigen precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB008538.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB008538.1, BC061970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCATCTA AAGGGTCCCC TTCTTGCCGT CTGGTTTTCT GCCTCTTGAT CTCCGCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_113941.1 |
CDS | 189..1940 |
Translation |
Target ORF information:
Target ORF information:
|
NM_031753.1 |
1 | ATGGCATCTA AAGGGTCCCC TTCTTGCCGT CTGGTTTTCT GCCTCTTGAT CTCCGCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa57724 | |
Clone ID Related Accession (Same CDS sequence) | XM_017598076.1 | |
Accession Version | XM_017598076.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1743bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | CD166 antigen isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACTCAC AGAGACTACA GCAGCGTGCT CCAGGACTAC GTGGTTCTGC ACCAGGTCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017453565.1 |
CDS | 278..2020 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017598076.1 |
1 | ATGAACTCAC AGAGACTACA GCAGCGTGCT CCAGGACTAC GTGGTTCTGC ACCAGGTCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa57725 | |
Clone ID Related Accession (Same CDS sequence) | XM_017598077.1 | |
Accession Version | XM_017598077.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | CD166 antigen isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATCTA AAGGGTCCCC TTCTTGCCGT CTGGTTTTCT GCCTCTTGAT CTCCGCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017453566.1 |
CDS | 583..2295 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017598077.1 |
1 | ATGGCATCTA AAGGGTCCCC TTCTTGCCGT CTGGTTTTCT GCCTCTTGAT CTCCGCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Activated leukocyte cell adhesion molecule is involved in excitatory synaptic transmission and plasticity in the rat spinal dorsal horn. |
Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction. |
Activated leukocyte cell adhesion molecule modulates neurotrophin signaling. |
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation. |
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. |