Gene Symbol | Gnb2 |
Entrez Gene ID | 81667 |
Full Name | G protein subunit beta 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | modulates calcium channel activity [RGD, Feb 2006]. |
ORF » Species Summary » Rattus norvegicus » Gnb2 cDNA ORF clone
gRNAs
Gene Symbol | Gnb2 |
Entrez Gene ID | 81667 |
Full Name | G protein subunit beta 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | modulates calcium channel activity [RGD, Feb 2006]. |
mRNA | Protein | Name |
---|---|---|
NM_031037.2 | NP_112299.1 | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 |
Danio rerio (zebrafish) | gnb2 | NP_001013515.1 |
Homo sapiens (human) | GNB2 | NP_005264.2 |
Pan troglodytes (chimpanzee) | GNB2 | XP_001152250.1 |
Canis lupus familiaris (dog) | GNB2 | XP_536861.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005913 | XP_315943.3 |
Rattus norvegicus (Norway rat) | Gnb2 | NP_112299.1 |
Bos taurus (cattle) | GNB2 | NP_001091030.1 |
Mus musculus (house mouse) | Gnb2 | NP_034442.1 |
G?? mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons.
Hern?ndez-Castellanos JM, Vivas O, Gardu?o J, De la Cruz L, Arenas I, El?as-Vi?as D, Mackie K, Garc?a DE
Biochemical and biophysical research communications445(1)250-4(2014 Feb)
KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.
Ahmed SM, Th?riault BL, Uppalapati M, Chiu CW, Gallie BL, Sidhu SS, Angers S
The Journal of cell biology199(6)951-67(2012 Dec)
G?2 and G?4 participate in the opioid and adrenergic receptor-mediated Ca2+ channel modulation in rat sympathetic neurons.
Mahmoud S, Yun JK, Ruiz-Velasco V
The Journal of physiology590(19)4673-89(2012 Oct)
G?? and the C terminus of SNAP-25 are necessary for long-term depression of transmitter release.
Zhang XL, Upreti C, Stanton PK
PloS one6(5)e20500(2011)
Enhanced expression of heterotrimeric GTP-binding protein subunits in Zajdela ascitic hepatoma.
Sharma SK, Das MR
Indian journal of biochemistry & biophysics39(3)148-54(2002 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate that verexpression of Gbeta2 subunit mimics CaV2.2 kinetic slowing by noradrenaline.
Title: G?? mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons.
Gnb2 and Gnb4 participate in the opioid and adrenergic receptor-mediated Ca2+ channel modulation in rat sympathetic neurons
Title: G?2 and G?4 participate in the opioid and adrenergic receptor-mediated Ca2+ channel modulation in rat sympathetic neurons.
Data show that the C-terminus of SNAP-25 is a binding target for Gbetagamma necessary for both transient transmitter-mediated presynaptic inhibition, and the induction of presynaptic LTD.
Title: G?? and the C terminus of SNAP-25 are necessary for long-term depression of transmitter release.
analysis of enhanced expression of heterotrimeric GTP-binding protein subunits in Zajdela ascitic hepatoma
Title: Enhanced expression of heterotrimeric GTP-binding protein subunits in Zajdela ascitic hepatoma.
The following Gnb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gnb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13196 | |
Clone ID Related Accession (Same CDS sequence) | NM_031037.2 | |
Accession Version | NM_031037.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC065579.1. On Feb 1, 2004 this sequence version replaced NM_031037.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGTGAGC TGGAGCAACT GAGACAGGAG GCTGAGCAGC TCCGGAACCA GATCCGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_112299.1 |
CDS | 229..1251 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGTGAGC TGGAGCAACT GAGACAGGAG GCTGAGCAGC TCCGGAACCA GATCCGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
G?? mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons. |
KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. |
G?2 and G?4 participate in the opioid and adrenergic receptor-mediated Ca2+ channel modulation in rat sympathetic neurons. |
G?? and the C terminus of SNAP-25 are necessary for long-term depression of transmitter release. |
Enhanced expression of heterotrimeric GTP-binding protein subunits in Zajdela ascitic hepatoma. |