Mmp24 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Mmp24 |
| Entrez Gene ID | 83513 |
| Full Name | matrix metallopeptidase 24 |
| Synonyms | MT5MMP,MTMMP5,Mt5-mmp |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | mouse homolog is a membrane-type matrix metalloproteinase; may play an important role in brain and during embryonic development [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_031757.1 | NP_113945.1 | matrix metalloproteinase-24 precursor |
| Homo sapiens (human) | MMP24 | NP_006681.1 |
| Rattus norvegicus (Norway rat) | Mmp24 | NP_113945.1 |
| MMP24 | XP_001100890.2 | |
| Danio rerio (zebrafish) | mmp24 | XP_699803.4 |
| Xenopus tropicalis (tropical clawed frog) | mmp24 | XP_002942325.2 |
| Canis lupus familiaris (dog) | MMP24 | XP_005635025.1 |
| Bos taurus (cattle) | MMP24 | XP_002692352.2 |
| Pan troglodytes (chimpanzee) | MMP24 | XP_003316927.1 |
| Mus musculus (house mouse) | Mmp24 | NP_034938.3 |
| Gallus gallus (chicken) | MMP24 | XP_417326.4 |
Related articles in PubMed
MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.
Porlan E, Mart?-Prado B, Morante-Redolat JM, Consiglio A, Delgado AC, Kypta R, L?pez-Ot?n C, Kirstein M, Fari?as I
Nature cell biology16(7)629-38(2014 Jul)
MT5-MMP, ADAM-10, and N-cadherin act in concert to facilitate synapse reorganization after traumatic brain injury.
Warren KM, Reeves TM, Phillips LL
Journal of neurotrauma29(10)1922-40(2012 Jul)
Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation.
Folgueras AR, Vald?s-S?nchez T, Llano E, Men?ndez L, Baamonde A, Denlinger BL, Belmonte C, Ju?rez L, Lastra A, Garc?a-Su?rez O, Astudillo A, Kirstein M, Pend?s AM, Fari?as I, L?pez-Ot?n C
Proceedings of the National Academy of Sciences of the United States of America106(38)16451-6(2009 Sep)
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Membrane localization of membrane type 5 matrix metalloproteinase by AMPA receptor binding protein and cleavage of cadherins.
Monea S, Jordan BA, Srivastava S, DeSouza S, Ziff EB
The Journal of neuroscience : the official journal of the Society for Neuroscience26(8)2300-12(2006 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Time- and injury-dependent expression of MT5-MMP, ADAM-10, and N-cadherin are confirmed during reactive synaptogenesis.
Title: MT5-MMP, ADAM-10, and N-cadherin act in concert to facilitate synapse reorganization after traumatic brain injury.
These results suggest that ABP directs MT5-MMP proteolytic activity to growth cones and synaptic sites in neurons, where it may regulate axon pathfinding or synapse remodeling through proteolysis of cadherins or other ECM or cell adhesion molecules.
Title: Membrane localization of membrane type 5 matrix metalloproteinase by AMPA receptor binding protein and cleavage of cadherins.
The following Mmp24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mmp24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa08665 | |
| Clone ID Related Accession (Same CDS sequence) | NM_031757.1 | |
| Accession Version | NM_031757.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | matrix metalloproteinase-24 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB023659.1. ##Evidence-Data-START## Transcript exon combination :: AB023659.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN02642596, SAMN02642603 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCCAAGGA GCCGGGGCGG CCGCGCTGCG CCGGGCCAGG CCGCGCGCTG GAGCGGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_113945.1 |
| CDS | 102..1958 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_031757.1 |
ORF Insert Sequence:
1 | ATGCCAAGGA GCCGGGGCGG CCGCGCTGCG CCGGGCCAGG CCGCGCGCTG GAGCGGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin. |
|
MT5-MMP, ADAM-10, and N-cadherin act in concert to facilitate synapse reorganization after traumatic brain injury. |
|
Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation. |
|
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
|
Membrane localization of membrane type 5 matrix metalloproteinase by AMPA receptor binding protein and cleavage of cadherins. |