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shox2 cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Summary

Gene Symbol shox2
Entrez Gene ID 100101703
Full Name short stature homeobox 2
Synonyms og12,og12x,ogi2x,shot
General protein information
Preferred Names

short stature homeobox 2

Names

short stature homeobox protein 2
Gene Type protein-coding
Organism Xenopus tropicalis(tropical clawed frog)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_012962582.2 XP_012818036.1 short stature homeobox protein 2 isoform X1
XM_012962582.3 XP_012818036.1 short stature homeobox protein 2 isoform X1
NM_001100224.1 NP_001093694.1 short stature homeobox protein 2

Pathways from BioSystems


Homologies


Homo sapiens (human) SHOX2 NP_003021.3
Canis lupus familiaris (dog) SHOX2 XP_542854.4
Bos taurus (cattle) SHOX2 NP_001192456.1
Gallus gallus (chicken) SHOX2 XP_003641845.2
Danio rerio (zebrafish) shox2 NP_957490.1
SHOX2 XP_001102324.1
Mus musculus (house mouse) Shox2 NP_038693.1
Rattus norvegicus (Norway rat) Shox2 NP_037160.1
Pan troglodytes (chimpanzee) SHOX2 XP_001153180.1
Xenopus tropicalis (tropical clawed frog) shox2 NP_001093694.1

Gene Ontology


Bibliography

Related articles in PubMed

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart.
Puskaric S, Schmitteckert S, Mori AD, Glaser A, Schneider KU, Bruneau BG, Blaschke RJ, Steinbeisser H, Rappold G
Human molecular genetics19(23)4625-33(2010 Dec)

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

work establishes a link between Tbx5, Shox2 and Bmp4 in the pacemaker region of the developing heart
Title: Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart.

The following shox2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the shox2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OXa22988 NM_001100224.1
Latest version!		 Xenopus tropicalis short stature homeobox 2 (shox2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $174.30
$249.00
OXa30226 XM_012962582.3
Latest version!		 Xenopus tropicalis short stature homeobox 2 (shox2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OXa30226 XM_012962582.2 Xenopus tropicalis short stature homeobox 2 (shox2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $174.30
$249.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OXa30226
Clone ID Related Accession (Same CDS sequence) XM_012962582.2 , XM_012962582.3
Accession Version XM_012962582.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 900bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-09-07
Organism Xenopus tropicalis(tropical clawed frog)
Product short stature homeobox protein 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_030681.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2016 this sequence version replaced XM_012962582.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Xenopus tropicalis Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAAGAAC TTACTGCTTT TGTGTCCAAG TCATTTGATC AGAAGATCAA GGAGAAGAAG 
GAGATGATCA CTTACCGGGA GGTGTTGGAA AGCGGCCCAG CTCGGGGCAA GGAGCCTGGC 
TGCGGAGAAG GGGCCCGGGA GGACGGACTA GCGGGGAACC GGTGTATAGG AGGGGGTGGC 
GGCGGTGGAG GAGGTGGTGG AGGGGCCAGA TCCCCGGTCT TGGAGCTCGA TCTGTCCGTG 
GAGAGGATCA GGGAGAGTGG AAGCCCGAAG CTCACTGAGG TATCCCCAGA GATAAAGGAA 
CGGAAGGAGG AGCTGAAGCA GCAGGCACTG GAGGAAGAGG GACAGACTAA GATCAAGCAG 
AGAAGGAGTC GGACTAACTT CACCCTGGAG CAGCTGAATG AGCTGGAGAG ATTGTTTGAT 
GAGACCCACT ACCCAGATGC CTTCATGAGG GAGGAGTTGA GCCAGCGCCT TGGCCTGTCA 
GAGGCCAGAG TTCAGGTCTG GTTTCAAAAC AGAAGGGCAA AATGCAGAAA ACAAGAAAAT 
CAGCTCCATA AAGGGGTCCT GATAGGAGCA GGGAGCCAGT TTGAAGCGTG TAGAGTCGCA 
CCTTATGTCA ATGTGGGAGC CCTGAGGATG CCATTCCAGC AGGTTCAGGC ACAGTTGCAG 
CTGGACAGCG CCGTGGCCCA CGCCCACCAC CACCTCCATC CTCACCTGAC GGCGCATGCG 
CCCTACATGA TGTTCCCGGC CCCGCCCTTC GGACTCCCGC TGGCGACACT GGCTGCGGAG 
ACGGCGACGG CAGCGTCTGT AGTTGCGGCA GCTGCGGCTG CTAAAACCTC TAGCAAGAAC 
TCGAGCATTG CAGATCTTAG ACTTAAAGCC AAAAAACACG CAGCAGCTCT AGGACTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_012818036.1
CDS396..1295
Translation

Target ORF information:

RefSeq Version XM_012962582.2
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis short stature homeobox 2 (shox2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_012962582.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAAGAAC TTACTGCTTT TGTGTCCAAG TCATTTGATC AGAAGATCAA GGAGAAGAAG 
GAGATGATCA CTTACCGGGA GGTGTTGGAA AGCGGCCCAG CTCGGGGCAA GGAGCCTGGC 
TGCGGAGAAG GGGCCCGGGA GGACGGACTA GCGGGGAACC GGTGTATAGG AGGGGGTGGC 
GGCGGTGGAG GAGGTGGTGG AGGGGCCAGA TCCCCGGTCT TGGAGCTCGA TCTGTCCGTG 
GAGAGGATCA GGGAGAGTGG AAGCCCGAAG CTCACTGAGG TATCCCCAGA GATAAAGGAA 
CGGAAGGAGG AGCTGAAGCA GCAGGCACTG GAGGAAGAGG GACAGACTAA GATCAAGCAG 
AGAAGGAGTC GGACTAACTT CACCCTGGAG CAGCTGAATG AGCTGGAGAG ATTGTTTGAT 
GAGACCCACT ACCCAGATGC CTTCATGAGG GAGGAGTTGA GCCAGCGCCT TGGCCTGTCA 
GAGGCCAGAG TTCAGGTCTG GTTTCAAAAC AGAAGGGCAA AATGCAGAAA ACAAGAAAAT 
CAGCTCCATA AAGGGGTCCT GATAGGAGCA GGGAGCCAGT TTGAAGCGTG TAGAGTCGCA 
CCTTATGTCA ATGTGGGAGC CCTGAGGATG CCATTCCAGC AGGTTCAGGC ACAGTTGCAG 
CTGGACAGCG CCGTGGCCCA CGCCCACCAC CACCTCCATC CTCACCTGAC GGCGCATGCG 
CCCTACATGA TGTTCCCGGC CCCGCCCTTC GGACTCCCGC TGGCGACACT GGCTGCGGAG 
ACGGCGACGG CAGCGTCTGT AGTTGCGGCA GCTGCGGCTG CTAAAACCTC TAGCAAGAAC 
TCGAGCATTG CAGATCTTAG ACTTAAAGCC AAAAAACACG CAGCAGCTCT AGGACTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OXa22988
Clone ID Related Accession (Same CDS sequence) NM_001100224.1
Accession Version NM_001100224.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 936bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-21
Organism Xenopus tropicalis(tropical clawed frog)
Product short stature homeobox protein 2
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ675518.1. ##Evidence-Data-START## Transcript exon combination :: DQ675518.1, DR894820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00028294, SAMD00028298 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAAGAAC TTACTGCTTT TGTGTCCAAG TCATTTGATC AGAAGATCAA GGAGAAGAAG 
GAGATGATCA CTTACCGGGA GGTGTTGGAA AGCGGCCCAG CTCGGGGCAA GGAGCCTGGC 
TGCGGAGAAG GGGCCCGGGA GGACGGACTA GCGGGGAACC GGTGTATAGG AGGGGGTGGC 
GGCGGTGGAG GAGGTGGTGG AGGGGCCAGA TCCCCGGTCT TGGAGCTCGA TCTGTCCGTG 
GAGAGGATCA GGGAGAGTGG AAGCCCGAAG CTCACTGAGG TATCCCCAGA GATAAAGGAA 
CGGAAGGAGG AGCTGAAGCA GCAGGCACTG GAGGAAGAGG GACAGACTAA GATCAAGCAG 
AGAAGGAGTC GGACTAACTT CACCCTGGAG CAGCTGAATG AGCTGGAGAG ATTGTTTGAT 
GAGACCCACT ACCCAGATGC CTTCATGAGG GAGGAGTTGA GCCAGCGCCT TGGCCTGTCA 
GAGGCCAGAG TTCAGGTCTG GTTTCAAAAC AGAAGGGCAA AATGCAGAAA ACAAGAAAAT 
CAGCTCCATA AAGGGGTCCT GATAGGAGCA GGGAGCCAGT TTGAAGCGTG TAGAGTCGCA 
CCTTATGTCA ATGTGGGAGC CCTGAGGATG CCATTCCAGC AGGATAGTCA TTGCAACGTG 
CCATCCTTGT CCTTCCAGGT TCAGGCACAG TTGCAGCTGG ACAGCGCCGT GGCCCACGCC 
CACCACCACC TCCATCCTCA CCTGACGGCG CATGCGCCCT ACATGATGTT CCCGGCCCCG 
CCCTTCGGAC TCCCGCTGGC GACACTGGCT GCGGAGACGG CGACGGCAGC GTCTGTAGTT 
GCGGCAGCTG CGGCTGCTAA AACCTCTAGC AAGAACTCGA GCATTGCAGA TCTTAGACTT 
AAAGCCAAAA AACACGCAGC AGCTCTAGGA CTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001093694.1
CDS156..1091
Translation

Target ORF information:

RefSeq Version NM_001100224.1
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis short stature homeobox 2 (shox2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001100224.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAAGAAC TTACTGCTTT TGTGTCCAAG TCATTTGATC AGAAGATCAA GGAGAAGAAG 
GAGATGATCA CTTACCGGGA GGTGTTGGAA AGCGGCCCAG CTCGGGGCAA GGAGCCTGGC 
TGCGGAGAAG GGGCCCGGGA GGACGGACTA GCGGGGAACC GGTGTATAGG AGGGGGTGGC 
GGCGGTGGAG GAGGTGGTGG AGGGGCCAGA TCCCCGGTCT TGGAGCTCGA TCTGTCCGTG 
GAGAGGATCA GGGAGAGTGG AAGCCCGAAG CTCACTGAGG TATCCCCAGA GATAAAGGAA 
CGGAAGGAGG AGCTGAAGCA GCAGGCACTG GAGGAAGAGG GACAGACTAA GATCAAGCAG 
AGAAGGAGTC GGACTAACTT CACCCTGGAG CAGCTGAATG AGCTGGAGAG ATTGTTTGAT 
GAGACCCACT ACCCAGATGC CTTCATGAGG GAGGAGTTGA GCCAGCGCCT TGGCCTGTCA 
GAGGCCAGAG TTCAGGTCTG GTTTCAAAAC AGAAGGGCAA AATGCAGAAA ACAAGAAAAT 
CAGCTCCATA AAGGGGTCCT GATAGGAGCA GGGAGCCAGT TTGAAGCGTG TAGAGTCGCA 
CCTTATGTCA ATGTGGGAGC CCTGAGGATG CCATTCCAGC AGGATAGTCA TTGCAACGTG 
CCATCCTTGT CCTTCCAGGT TCAGGCACAG TTGCAGCTGG ACAGCGCCGT GGCCCACGCC 
CACCACCACC TCCATCCTCA CCTGACGGCG CATGCGCCCT ACATGATGTT CCCGGCCCCG 
CCCTTCGGAC TCCCGCTGGC GACACTGGCT GCGGAGACGG CGACGGCAGC GTCTGTAGTT 
GCGGCAGCTG CGGCTGCTAA AACCTCTAGC AAGAACTCGA GCATTGCAGA TCTTAGACTT 
AAAGCCAAAA AACACGCAGC AGCTCTAGGA CTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OXa30226
Clone ID Related Accession (Same CDS sequence) XM_012962582.2 , XM_012962582.3
Accession Version XM_012962582.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 900bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-17
Organism Xenopus tropicalis(tropical clawed frog)
Product short stature homeobox protein 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_030681.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2019 this sequence version replaced XM_012962582.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Xenopus tropicalis Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAAGAAC TTACTGCTTT TGTGTCCAAG TCATTTGATC AGAAGATCAA GGAGAAGAAG 
GAGATGATCA CTTACCGGGA GGTGTTGGAA AGCGGCCCAG CTCGGGGCAA GGAGCCTGGC 
TGCGGAGAAG GGGCCCGGGA GGACGGACTA GCGGGGAACC GGTGTATAGG AGGGGGTGGC 
GGCGGTGGAG GAGGTGGTGG AGGGGCCAGA TCCCCGGTCT TGGAGCTCGA TCTGTCCGTG 
GAGAGGATCA GGGAGAGTGG AAGCCCGAAG CTCACTGAGG TATCCCCAGA GATAAAGGAA 
CGGAAGGAGG AGCTGAAGCA GCAGGCACTG GAGGAAGAGG GACAGACTAA GATCAAGCAG 
AGAAGGAGTC GGACTAACTT CACCCTGGAG CAGCTGAATG AGCTGGAGAG ATTGTTTGAT 
GAGACCCACT ACCCAGATGC CTTCATGAGG GAGGAGTTGA GCCAGCGCCT TGGCCTGTCA 
GAGGCCAGAG TTCAGGTCTG GTTTCAAAAC AGAAGGGCAA AATGCAGAAA ACAAGAAAAT 
CAGCTCCATA AAGGGGTCCT GATAGGAGCA GGGAGCCAGT TTGAAGCGTG TAGAGTCGCA 
CCTTATGTCA ATGTGGGAGC CCTGAGGATG CCATTCCAGC AGGTTCAGGC ACAGTTGCAG 
CTGGACAGCG CCGTGGCCCA CGCCCACCAC CACCTCCATC CTCACCTGAC GGCGCATGCG 
CCCTACATGA TGTTCCCGGC CCCGCCCTTC GGACTCCCGC TGGCGACACT GGCTGCGGAG 
ACGGCGACGG CAGCGTCTGT AGTTGCGGCA GCTGCGGCTG CTAAAACCTC TAGCAAGAAC 
TCGAGCATTG CAGATCTTAG ACTTAAAGCC AAAAAACACG CAGCAGCTCT AGGACTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_012818036.1
CDS417..1316
Translation

Target ORF information:

RefSeq Version XM_012962582.3
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis short stature homeobox 2 (shox2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_012962582.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAAGAAC TTACTGCTTT TGTGTCCAAG TCATTTGATC AGAAGATCAA GGAGAAGAAG 
GAGATGATCA CTTACCGGGA GGTGTTGGAA AGCGGCCCAG CTCGGGGCAA GGAGCCTGGC 
TGCGGAGAAG GGGCCCGGGA GGACGGACTA GCGGGGAACC GGTGTATAGG AGGGGGTGGC 
GGCGGTGGAG GAGGTGGTGG AGGGGCCAGA TCCCCGGTCT TGGAGCTCGA TCTGTCCGTG 
GAGAGGATCA GGGAGAGTGG AAGCCCGAAG CTCACTGAGG TATCCCCAGA GATAAAGGAA 
CGGAAGGAGG AGCTGAAGCA GCAGGCACTG GAGGAAGAGG GACAGACTAA GATCAAGCAG 
AGAAGGAGTC GGACTAACTT CACCCTGGAG CAGCTGAATG AGCTGGAGAG ATTGTTTGAT 
GAGACCCACT ACCCAGATGC CTTCATGAGG GAGGAGTTGA GCCAGCGCCT TGGCCTGTCA 
GAGGCCAGAG TTCAGGTCTG GTTTCAAAAC AGAAGGGCAA AATGCAGAAA ACAAGAAAAT 
CAGCTCCATA AAGGGGTCCT GATAGGAGCA GGGAGCCAGT TTGAAGCGTG TAGAGTCGCA 
CCTTATGTCA ATGTGGGAGC CCTGAGGATG CCATTCCAGC AGGTTCAGGC ACAGTTGCAG 
CTGGACAGCG CCGTGGCCCA CGCCCACCAC CACCTCCATC CTCACCTGAC GGCGCATGCG 
CCCTACATGA TGTTCCCGGC CCCGCCCTTC GGACTCCCGC TGGCGACACT GGCTGCGGAG 
ACGGCGACGG CAGCGTCTGT AGTTGCGGCA GCTGCGGCTG CTAAAACCTC TAGCAAGAAC 
TCGAGCATTG CAGATCTTAG ACTTAAAGCC AAAAAACACG CAGCAGCTCT AGGACTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart.
Human molecular genetics19(23)4625-33(2010 Dec)
Puskaric S,Schmitteckert S,Mori AD,Glaser A,Schneider KU,Bruneau BG,Blaschke RJ,Steinbeisser H,Rappold G


book

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P