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mmadhc cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Summary

Gene Symbol mmadhc
Entrez Gene ID 549485
Full Name methylmalonic aciduria and homocystinuria, cblD type
General protein information
Preferred Names

methylmalonic aciduria and homocystinuria, cblD type

Names

methylmalonic aciduria and homocystinuria type D protein, mitochondrial
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
Gene Type protein-coding
Organism Xenopus tropicalis(tropical clawed frog)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001016731.2 NP_001016731.1 methylmalonic aciduria and homocystinuria type D protein, mitochondrial
XM_018097111.2 XP_017952600.2 methylmalonic aciduria and homocystinuria type D protein, mitochondrial isoform X1
XM_018097111.1 XP_017952600.1 methylmalonic aciduria and homocystinuria type D protein, mitochondrial isoform X1

Pathways from BioSystems


Homologies


Homo sapiens (human) MMADHC NP_056517.1
Bos taurus (cattle) MMADHC NP_001029713.1
Gallus gallus (chicken) MMADHC NP_001008477.1
Caenorhabditis elegans (roundworm) Y76A2B.5 NP_499801.1
MMADHC XP_001082223.1
Mus musculus (house mouse) Mmadhc NP_598600.1
Rattus norvegicus (Norway rat) Mmadhc NP_001004280.1
Xenopus tropicalis (tropical clawed frog) mmadhc NP_001016731.1
Pan troglodytes (chimpanzee) MMADHC XP_001135306.1
Canis lupus familiaris (dog) MMADHC XP_849074.1
Danio rerio (zebrafish) zgc:92335 NP_001002453.1

Gene Ontology


Bibliography

Related articles in PubMed

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following mmadhc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mmadhc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OXa25614 NM_001016731.2
Latest version!		 Xenopus tropicalis metabolism of cobalamin associated D (mmadhc), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $174.30
$249.00
OXa25614 XM_018097111.2
Latest version!		 Xenopus tropicalis metabolism of cobalamin associated D (mmadhc), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OXa46586 XM_018097111.1
Latest version!		 Xenopus tropicalis methylmalonic aciduria and homocystinuria, cblD type (mmadhc), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $174.30
$249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OXa25614
Clone ID Related Accession (Same CDS sequence) NM_001016731.2 , XM_018097111.2
Accession Version NM_001016731.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 894bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-22
Organism Xenopus tropicalis(tropical clawed frog)
Product methylmalonic aciduria and homocystinuria type D protein, mitochondrial
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CR760028.2. On Oct 14, 2005 this sequence version replaced NM_001016731.1. ##Evidence-Data-START## Transcript exon combination :: CR760028.2, BX716075.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00028290, SAMD00028291 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCTAATG CCCTATGTAG CAGAGCCAGA CTGGTGACCT ACCTCCCTAG GTTTAGTTCA 
TTGATTAGAA GGGTCTCAGG TACCCGGGCC TTTTCCACAG CAGGATCTTC AGGCTCTGAT 
GAGCCTTACA TTGCTGCTAC ACCTCCTGAT ATACTTCCCA GGACAGTATG GCCCGATGAG 
ACAATGGGCC CATTTGGCCC ACAAGACCAG CGCTTTCAGC TTCCAGGTAA TGTAGGATTT 
GATGCCCACG TGAATGGAAT AGACATTAAG AGGAGAATAG AAGTCAATAG AAATCTTCCG 
GACCTGCTGA CTGAGCCTCA ACCAAGTGAA AGGCATGAAT TTGTAATGGC CCAGTTTGTG 
ACTGAATTCC AGGGGAGTGA AGTTTCACTA GAGCCGCAGG AATTAAACAC TATGGAAAGC 
TACTTTGAAA ATGCAAAGGT GGAATGTGCA ATGCAGTCTT GTCCTGATCT GCTGAAAAAA 
GATTTTGCTT CTATGTTTCC TGAAATCCCC AGCAATAATT TAATGGTGCT AACAGTTACT 
CAGAGGACAC ACAATGATAT GACAATTTGG AGTCAAGAGG TGGAAAATGA GAGGGAAATG 
TTAATAGAAA AGTTCATGAA CGGTGCCAAA GAGATTTGCT ACGCGCTAAG GACAGAAGGA 
TACTGGGCGG ACTTTATTGA CCCACTGTCG GGACTTGCAT ATTTTGGGCC TTACACAAAC 
AACACGCTGT TTGAAACAGA TGAGCGATAT CGCCACCTGG GATTCAAAGT GGAGGACCTG 
GGGTGCTGTA AAGTGATTCG CCACAATGTC TGGGGAACAC ATGTAGTTGT GGGAAGTATA 
TTTACCAACG CCCCCTCAGA CAGTCCTATC ATGAAGAAAC TGGGGGAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001016731.1
CDS83..976
Translation

Target ORF information:

RefSeq Version NM_001016731.2
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis metabolism of cobalamin associated D (mmadhc), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001016731.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCTAATG CCCTATGTAG CAGAGCCAGA CTGGTGACCT ACCTCCCTAG GTTTAGTTCA 
TTGATTAGAA GGGTCTCAGG TACCCGGGCC TTTTCCACAG CAGGATCTTC AGGCTCTGAT 
GAGCCTTACA TTGCTGCTAC ACCTCCTGAT ATACTTCCCA GGACAGTATG GCCCGATGAG 
ACAATGGGCC CATTTGGCCC ACAAGACCAG CGCTTTCAGC TTCCAGGTAA TGTAGGATTT 
GATGCCCACG TGAATGGAAT AGACATTAAG AGGAGAATAG AAGTCAATAG AAATCTTCCG 
GACCTGCTGA CTGAGCCTCA ACCAAGTGAA AGGCATGAAT TTGTAATGGC CCAGTTTGTG 
ACTGAATTCC AGGGGAGTGA AGTTTCACTA GAGCCGCAGG AATTAAACAC TATGGAAAGC 
TACTTTGAAA ATGCAAAGGT GGAATGTGCA ATGCAGTCTT GTCCTGATCT GCTGAAAAAA 
GATTTTGCTT CTATGTTTCC TGAAATCCCC AGCAATAATT TAATGGTGCT AACAGTTACT 
CAGAGGACAC ACAATGATAT GACAATTTGG AGTCAAGAGG TGGAAAATGA GAGGGAAATG 
TTAATAGAAA AGTTCATGAA CGGTGCCAAA GAGATTTGCT ACGCGCTAAG GACAGAAGGA 
TACTGGGCGG ACTTTATTGA CCCACTGTCG GGACTTGCAT ATTTTGGGCC TTACACAAAC 
AACACGCTGT TTGAAACAGA TGAGCGATAT CGCCACCTGG GATTCAAAGT GGAGGACCTG 
GGGTGCTGTA AAGTGATTCG CCACAATGTC TGGGGAACAC ATGTAGTTGT GGGAAGTATA 
TTTACCAACG CCCCCTCAGA CAGTCCTATC ATGAAGAAAC TGGGGGAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OXa25614
Clone ID Related Accession (Same CDS sequence) NM_001016731.2 , XM_018097111.2
Accession Version XM_018097111.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 894bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-17
Organism Xenopus tropicalis(tropical clawed frog)
Product methylmalonic aciduria and homocystinuria type D protein, mitochondrial isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_030685.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2019 this sequence version replaced XM_018097111.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Xenopus tropicalis Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCTAATG CCCTATGTAG CAGAGCCAGA CTGGTGACCT ACCTCCCTAG GTTTAGTTCA 
TTGATTAGAA GGGTCTCAGG TACCCGGGCC TTTTCCACAG CAGGATCTTC AGGCTCTGAT 
GAGCCTTACA TTGCTGCTAC ACCTCCTGAT ATACTTCCCA GGACAGTATG GCCCGATGAG 
ACAATGGGCC CATTTGGCCC ACAAGACCAG CGCTTTCAGC TTCCAGGTAA TGTAGGATTT 
GATGCCCACG TGAATGGAAT AGACATTAAG AGGAGAATAG AAGTCAATAG AAATCTTCCG 
GACCTGCTGA CTGAGCCTCA ACCAAGTGAA AGGCATGAAT TTGTAATGGC CCAGTTTGTG 
ACTGAATTCC AGGGGAGTGA AGTTTCACTA GAGCCGCAGG AATTAAACAC TATGGAAAGC 
TACTTTGAAA ATGCAAAGGT GGAATGTGCA ATGCAGTCTT GTCCTGATCT GCTGAAAAAA 
GATTTTGCTT CTATGTTTCC TGAAATCCCC AGCAATAATT TAATGGTGCT AACAGTTACT 
CAGAGGACAC ACAATGATAT GACAATTTGG AGTCAAGAGG TGGAAAATGA GAGGGAAATG 
TTAATAGAAA AGTTCATGAA CGGTGCCAAA GAGATTTGCT ACGCGCTAAG GACAGAAGGA 
TACTGGGCGG ACTTTATTGA CCCACTGTCG GGACTTGCAT ATTTTGGGCC TTACACAAAC 
AACACGCTGT TTGAAACAGA TGAGCGATAT CGCCACCTGG GATTCAAAGT GGAGGACCTG 
GGGTGCTGTA AAGTGATTCG CCACAATGTC TGGGGAACAC ATGTAGTTGT GGGAAGTATA 
TTTACCAACG CCCCCTCAGA CAGTCCTATC ATGAAGAAAC TGGGGGAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017952600.2
CDS299..1192
Translation

Target ORF information:

RefSeq Version XM_018097111.2
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis metabolism of cobalamin associated D (mmadhc), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_018097111.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCTAATG CCCTATGTAG CAGAGCCAGA CTGGTGACCT ACCTCCCTAG GTTTAGTTCA 
TTGATTAGAA GGGTCTCAGG TACCCGGGCC TTTTCCACAG CAGGATCTTC AGGCTCTGAT 
GAGCCTTACA TTGCTGCTAC ACCTCCTGAT ATACTTCCCA GGACAGTATG GCCCGATGAG 
ACAATGGGCC CATTTGGCCC ACAAGACCAG CGCTTTCAGC TTCCAGGTAA TGTAGGATTT 
GATGCCCACG TGAATGGAAT AGACATTAAG AGGAGAATAG AAGTCAATAG AAATCTTCCG 
GACCTGCTGA CTGAGCCTCA ACCAAGTGAA AGGCATGAAT TTGTAATGGC CCAGTTTGTG 
ACTGAATTCC AGGGGAGTGA AGTTTCACTA GAGCCGCAGG AATTAAACAC TATGGAAAGC 
TACTTTGAAA ATGCAAAGGT GGAATGTGCA ATGCAGTCTT GTCCTGATCT GCTGAAAAAA 
GATTTTGCTT CTATGTTTCC TGAAATCCCC AGCAATAATT TAATGGTGCT AACAGTTACT 
CAGAGGACAC ACAATGATAT GACAATTTGG AGTCAAGAGG TGGAAAATGA GAGGGAAATG 
TTAATAGAAA AGTTCATGAA CGGTGCCAAA GAGATTTGCT ACGCGCTAAG GACAGAAGGA 
TACTGGGCGG ACTTTATTGA CCCACTGTCG GGACTTGCAT ATTTTGGGCC TTACACAAAC 
AACACGCTGT TTGAAACAGA TGAGCGATAT CGCCACCTGG GATTCAAAGT GGAGGACCTG 
GGGTGCTGTA AAGTGATTCG CCACAATGTC TGGGGAACAC ATGTAGTTGT GGGAAGTATA 
TTTACCAACG CCCCCTCAGA CAGTCCTATC ATGAAGAAAC TGGGGGAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OXa46586
Clone ID Related Accession (Same CDS sequence) XM_018097111.1
Accession Version XM_018097111.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 894bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-09-07
Organism Xenopus tropicalis(tropical clawed frog)
Product methylmalonic aciduria and homocystinuria type D protein, mitochondrial isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_030685.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Xenopus tropicalis Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCTAATG CCCTATGTAG CAGAGCCAGA CTGGTGACCT ACCTCCCTAG GTTTAGTTTG 
TTGATTAGAA GGGTCTCAGG TACCCGGGCC TTTTCCACAG CAGGATCTTC AGGCTCTGAT 
GAGCCTTACA TTGCTGCTAC ACCTCCTGAT ATACTTCCCA GGACAGTATG GCCCGATGAG 
ACAATGGGCC CCTTTGGCCC ACAAGACCAG CGCTTTCAGC TTCCAGGTAA TGTAGGATTT 
GATGCCCACG TGAATGGAAT AGACATTAAG AGGAGAATAG AAGTCAATAG AAATCTTCCG 
GACCTGCTGA CTGAGCCTCA ACCGAGTGAA AGGCATGAAT TTGTAATGGC CCAGTTTGTG 
ACTGAATTCC AGGGGAGTGA AGTTTCGCTA GAGCCGCAGG AATTAAACAC TATGGAAAGC 
TACTTTGAAA ATGCAAAGGT GGAATGTGCA ATGCAGTCTT GTCCTGATCT GCTGAAAAAA 
GATTTTGCTT CTATGTTTCC TGAAATCCCC AGCAATAATT TAATGGTGCT AACAGTTACT 
CAGAGGACAC ACAATGATAT GACAATTTGG AGTCAAGAGG TGGAAAATGA GAGGGAAATG 
TTAATAGAAA AGTTCATGAA CGGTGCCAAA GAGATTTGCT ACGCGCTAAG GACAGAAGGA 
TACTGGGCGG ACTTTATTGA CCCACTGTCG GGACTTGCAT ATTTTGGGCC TTACACAAAC 
AACACGCTGT TTGAAACAGA TGAGCGATAT CGCCACCTGG GATTCAAAGT GGAGGACCTG 
GGGTGCTGTA AAGTGATTCG CCACAATGTC TGGGGAACAC ATGTAGTTGT GGGAAGTATA 
TTTACCAACG CCCCCTCAGA CAGTCCTATC ATGAAGAAAC TGGGGGAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017952600.1
CDS354..1247
Translation

Target ORF information:

RefSeq Version XM_018097111.1
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis methylmalonic aciduria and homocystinuria, cblD type (mmadhc), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_018097111.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCTAATG CCCTATGTAG CAGAGCCAGA CTGGTGACCT ACCTCCCTAG GTTTAGTTTG 
TTGATTAGAA GGGTCTCAGG TACCCGGGCC TTTTCCACAG CAGGATCTTC AGGCTCTGAT 
GAGCCTTACA TTGCTGCTAC ACCTCCTGAT ATACTTCCCA GGACAGTATG GCCCGATGAG 
ACAATGGGCC CCTTTGGCCC ACAAGACCAG CGCTTTCAGC TTCCAGGTAA TGTAGGATTT 
GATGCCCACG TGAATGGAAT AGACATTAAG AGGAGAATAG AAGTCAATAG AAATCTTCCG 
GACCTGCTGA CTGAGCCTCA ACCGAGTGAA AGGCATGAAT TTGTAATGGC CCAGTTTGTG 
ACTGAATTCC AGGGGAGTGA AGTTTCGCTA GAGCCGCAGG AATTAAACAC TATGGAAAGC 
TACTTTGAAA ATGCAAAGGT GGAATGTGCA ATGCAGTCTT GTCCTGATCT GCTGAAAAAA 
GATTTTGCTT CTATGTTTCC TGAAATCCCC AGCAATAATT TAATGGTGCT AACAGTTACT 
CAGAGGACAC ACAATGATAT GACAATTTGG AGTCAAGAGG TGGAAAATGA GAGGGAAATG 
TTAATAGAAA AGTTCATGAA CGGTGCCAAA GAGATTTGCT ACGCGCTAAG GACAGAAGGA 
TACTGGGCGG ACTTTATTGA CCCACTGTCG GGACTTGCAT ATTTTGGGCC TTACACAAAC 
AACACGCTGT TTGAAACAGA TGAGCGATAT CGCCACCTGG GATTCAAAGT GGAGGACCTG 
GGGTGCTGTA AAGTGATTCG CCACAATGTC TGGGGAACAC ATGTAGTTGT GGGAAGTATA 
TTTACCAACG CCCCCTCAGA CAGTCCTATC ATGAAGAAAC TGGGGGAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P