Discover how our Next-Generation CMOS Technology is pushing the boundaries of DNA Synthesis.
Miniature Semiconductor Chip (MSC) enables large-scale de novo synthesis of DNA using proprietary electrochemistry technologies and delivers precision on a microelectrode scale.
Semiconductor based ensures spatial control over the whole process
Less interference of H2O, O2, O3 and static electricity
Full chamber reaction with standard wafer and chip production process
We Offer Customized Pricing to Match your Needs (Starting from 1K pool size). Get an Estimated Price with Our Calculator Today!
Oligo Length (10-170nt)
Pool Size (0K - 8M)
CRISPR gRNA Library
Oligo pool gRNA libraries, utilizing CRISPR gene editing, enable high-throughput screening for cancer therapy, diagnostics, and microorganism engineering. They facilitate gene knock-out and activation, probing tumorigenesis, biomarkers, and metabolic pathways. This transformative tool leverages CRISPR's precision for versatile biomedical and biotech applications.
A pooled lentiviral screen can be performed to identify genes regulating cellular responses and signaling pathways, or to uncover novel functions. Libraries can comprise 50 to thousands of constructs. GenScript offers lentivirus-based RNAi libraries through our siRNA Design Center and chip-based synthesis platform, supporting research hypothesis verification.
NGS Target Enrichment
Next-generation sequencing (NGS) target enrichment utilizing oligo pools has emerged as a transformative technique in genomics research. By custom designing pools of oligonucleotide probes complementary to specific genomic regions of interest, researchers can efficiently capture and amplify relevant DNA fragments for sequencing. This approach not only streamlines the sequencing process but also significantly reduces the cost and data burden.
Protein & Antibody Engineering
Mutant libraries are powerful, high-throughput tools for optimizing protein structure and function. However, traditional methods for library construction, including error-prone PCR or degenerate methods, suffer from limited control over codon usage and poor variant representation. Powered by our semiconductor-based oligo synthesis technology, our Precision Mutant Library service offers precise control over each synthesized variant. The result is a more diverse and fully covered mutant library with unbiased distribution.
Library services we offer:
Gene Fragments offer a cost-effective, swift, and effective avenue for constructing the requisite genes in your research endeavors. These double-stranded DNA fragments of up to 1,800 base pairs in length, fulfilling the demands of easy gene construction or modification suitable for a variety of applications, including antibody development, CRISPR-mediated genome editing, and NGS controls. The GenTitan™ Gene Fragments Service leverages our exclusive complementary metal oxide semiconductor (CMOS) integrated circuits (IC), ensuring unmatched precision, accelerated delivery schedules, and exceptional cost-effectiveness.
DNA Data Storage
DNA data storage involves encoding digital information as DNA sequences, utilizing the four DNA bases (A, T, C, and G) to represent binary data (0s and 1s). These sequences can be later synthesized into DNA strands for storage. Oligo pools are used to generate these sequences efficiently and in parallel, allowing large amounts of data to be encoded using unique combinations of oligos.