Immuno-Oncology Research
Immuno-oncology (cancer immunotherapy), describes the process of utilizing the patient's own immune system to fight cancer. In the last decade, immuno-oncology has emerged as an exciting new approach to cancer treatment because of its specificity, adaptability and durability. One of the key areas within this field is a new class of proteins called immune checkpoints, such as PD-1 and CTLA-4 among others, which could enable cancer cells to hide from the immune system by modulating T cell signaling. Immune-checkpoints are being studied extensively as a new type of targets for cancer immunotherapy.
GenScript provides the One-Stop Platform to accelerate your immuno-oncology research, including numerous neutralizing immune checkpoint antibodies and anti-idiotypes (IDs), stable cell lines expressing immuno-oncology proteins at high levels, a wide range of purified recombinant proteins involved in immuno-signaling pathways, together with assay platforms for drug discovery and development.
| Immune Checkpoint Antibodies
GenScript provides multifunctional immune checkpoint antibody products to facilitate your immunotherapy research. |
Immuno-Oncology Recombination Proteins
The high-quality Immune Checkpoint Proteins in GenScript can support many kinds of researches in immune-oncology field |
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| ADCC & CDC assays
By implementing strict QC standards, GenScript provides the assurance of the efficacy and potency profiles of your therapeutic antibodies. |
Stable Cell Lines for Immuno-Oncology Research (CellPower™)
Both immune checkpoints and oncogene expressed stable cell lines are supplied; |
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| Tumor Cell Line Profiling
OncoProfiler and XenoProfiler not only provide efficacy data in human tumor cell lines, but also ensure translation of efficacy from in vitro to in vivo models. |
Animal Tumor Models
GenScript provides syngeneic tumor models, huPBMC engrafted tumor models and immune checkpoint humanized models for drug efficacy or proof-of-concept studies. |
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