MonoRab™ Rabbit Anti-Camelid VHH Antibody Plate (Clear, 8×12 strip)

The product is used for rapid capture of VHHs in different samples.

Price	$260.00
Cat. No.	L00946
Size	5 plates Buy in bulk
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Product Introduction Applications Background Bottom Notes

Product Introduction

Product Description	MonoRab™ Rabbit Anti-Camelid VHH Antibody Plate (Clear, 8×12 strip) (GenScript, L00946) is a 96-well microtiter plate coated with MonoRab™ Rabbit Anti-Camelid VHH Cocktail (GenScript, A02014). It can bind camelid and humanized VHHs with high specificity and capacity. The binding capacity and detection limits of plate varies, depending on the amino acid constitution of different VHH. The plate can be compatible with MonoRab™ Rabbit Anti-Camelid VHH Cocktail [HRP] (GenScript, A02016), HRP (Horseradish peroxidase) conjugated secondary antibody, or HRP-conjugated specific antigen. Any detection reagent, which can recognize Rabbit IgG, should not be applied to the plate, such as HRP-conjugated Mouse anti-Rabbit IgG and HRP-Protein A.
Binding capacity	~3 ng/well
Sensitivity	1 ng/ml
Specificity	Camelid (Alpaca and Llama) and humanized VHHs
Pre-coated Antibody	MonoRab™ Rabbit Anti-Camelid VHH Cocktail
Reagents compatibility	Compatible with common used reagents (see Reagent Compatibility table)
Storage	MonoRab™ Rabbit Anti-Camelid VHH Antibody Plate should be shipped on ice pack. The unopened plate is stable for 1 years when stored at 2-8 ℃. The opened plate should be used within one week.

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Applications

There are several potential applications for the plate:
1. Fix anti-VHH antibodies on the plate, which provides a universal platform to monitor the VHH level in different culture condition and to detect specific VHH for immunogenicity studies.
2. High throughput screening of stable cell lines expressing camelid or humanized VHHs.
3. Study the pharmacokinetics of camelid or humanized VHH antibody drugs in serum.
4. Detect the immuno-response of the heavy-chain-only antibody in camelid after immunization.

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Background

Background

Camelid VHH Antibody (also called single-domain antibody (sdAb), or Nanobody by Ablynx) is a peptide chain about 110 amino acids in length, containing one variable domain of a heavy-chain antibody (a VHH fragment). Like a whole antibody, the camelid VHH antibody is able to bind selectively to a specific antigen. Due to its small size, simple production and high affinity, the camelid VHH antibody has a broad range of applications in biotechnical and therapeutic research fields.

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For research use only. Not for use in diagnostic procedures