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CHO-K1/Tim3 Stable Cell Line

Figure 1. FACS analysis of Tim3 expression in CHO-K1/Tim3 cells.

CHO-K1/Tim3 Stable Cell Line

T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 amino acid mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 amino acid extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD.
M00531
$8,500.00

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Description

T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 amino acid mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 amino acid extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD.

Synonyms

HAVCR2 ; CD366; HAVcr-2; KIM-3; TIM3; TIMD-3; TIMD3

Overview
Applications Binding assay or use as immunogen

Product Introduction
Storage Liquid nitrogen immediately upon receiving
Species Human

Culture Conditions
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 8μg/ml Puromycin

Examples
  • CHO-K1/Tim3 Stable Cell Line
  • CHO-K1/Tim3 Stable Cell Line

    Figure 1. FACS analysis of Tim3 expression in CHO-K1/Tim3 cells.


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