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CHO-K1/BTLA Stable Cell Line

Figure 1. FACS analysis of BTLA expression in CHO-K1/BTLA cells.

CHO-K1/BTLA Stable Cell Line

The B and T lymphocyte attenuator (BTLA) is an Ig super family protein with an intermediate type Ig fold in the ectodomain and an ITIM inhibitory signaling domain in the cytosol. BTLA interacts with the herpesvirus entry mediator (HVEM; TNFRSF14), a TNFR super family member. Engagement of BTLA by HVEM, induces tyrosine phosphorylation of the ITIM motifs in the cytoplasmic tail of BTLA, allowing the recruitment of the phosphatases SHP-1 and SHP-2, which attenuate signaling.
M00534
$8,500.00

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Description

The B and T lymphocyte attenuator (BTLA) is an Ig super family protein with an intermediate type Ig fold in the ectodomain and an ITIM inhibitory signaling domain in the cytosol. BTLA interacts with the herpesvirus entry mediator (HVEM; TNFRSF14), a TNFR super family member. Engagement of BTLA by HVEM, induces tyrosine phosphorylation of the ITIM motifs in the cytoplasmic tail of BTLA, allowing the recruitment of the phosphatases SHP-1 and SHP-2, which attenuate signaling.

Synonyms

BTLA1; CD272

Overview
Applications Binding assay or use as immunogen

Product Introduction
Storage Liquid nitrogen immediately upon receiving
Species Human

Culture Conditions
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 600 μg/ml G418

Examples
  • CHO-K1/BTLA Stable Cell Line
  • CHO-K1/BTLA Stable Cell Line

    Figure 1. FACS analysis of BTLA expression in CHO-K1/BTLA cells.


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