|Synonyms||Cd152; Ly-56; Ctla-4|
|Description||CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. CTLA4 is constitutively expressed in Tregs but only upregulated in conventional T cells after activation. It acts as an `off` switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.|
|Culture Medium||F12K, 10% FBS, 8 μg/ml Puromycin|
|Freeze Medium||95% complete growth medium, 5% DMSO|
|Storage||Liquid nitrogen immediately upon delivery|
|Binding assay or use as immunogen
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