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CHO-K1/mouse ADORA2A Stable Cell Line

Synonyms RDC8; A2-AR; adenosine receptor A2a
Description The adenosine receptors ADORA2A are Gs-coupled GPCRs expressed in the thymus gland, heart, lung, kidney, brain, platelets, spleen and leukocytes. ADORA2A down-regulates chemokine receptor function and inhibits platelet aggregation. ADORA2A antagonists may be useful as therapy for Parkinson's disease.
Species mouse
Culture Medium F-12K, 10% FBS, 450 μg/ml Zeocin
Freeze Medium 95% complete growth medium, 5% DMSO

Stability 16 passages
Storage Liquid nitrogen immediately upon delivery

Functional assay for mouse ADORA2A receptor

  • CHO-K1/mouse ADORA2A Stable Cell Line
  • CHO-K1/mouse ADORA2A Stable Cell Line

    Dose dependent stimulation of intracellular cAMP mobilization upon treatment with NECA. The EC50 of NECA on CHO-K1/mouse ADORA2A cells was 9.57 nM.

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Cat. No. M00575
2 vials $8500.00