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CHO-K1/mouse PD-L2 Stable Cell Line

Synonyms Btdc; B7-DC; Pdcd1lg2; F730015O22Rik
Description Programmed cell death 1 ligand 2 (PD-L2) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs). PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on microenvironmental stimuli.
Species Mouse
Culture Medium F12K, 10% FBS, 8 μg/ml Puromycin
Freeze Medium 95% complete growth medium, 5% DMSO

Stability 15 passages
Storage Liquid nitrogen immediately upon receiving

CHO-K1/mouse PD-L2 Stable Cell Line
CHO-K1/mouse PD-L2 Stable Cell Line

FACS analysis of mouse PDL2 expression in CHO-K1 cells.

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Cat. No. M00628
2 vials $8500.00
24 hour