Catalog Products » Stable Cell Lines » Cyno Recombinant PD-L2 Stable Cell Line
CHO-K1/cyno PD-L2 Stable Cell Line

FACS analysis of cyno PD-L2 expression in CHO-K1 cells.

CHO-K1/cyno PD-L2 Stable Cell Line

Programmed cell death 1 ligand 2 (PD-L2) is a protein that is encoded by the PDCD1LG2 gene in humans. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs). However, PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on micro environmental stimuli.
M00629
$8,500.00

Ask us a question
Description

Programmed cell death 1 ligand 2 (PD-L2) is a protein that is encoded by the PDCD1LG2 gene in humans. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs). However, PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on micro environmental stimuli.

Synonyms

Btdc; B7-DC ; PDCD1LG2

Overview
Applications Binding assay or use as immunogen

Product Introduction
Storage Liquid nitrogen immediately upon receiving
Species Cyno
Stability 15 passages

Culture Conditions
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 8 μg/ml Puromycin

Examples
  • CHO-K1/cyno PD-L2 Stable Cell Line
  • CHO-K1/cyno PD-L2 Stable Cell Line

    FACS analysis of cyno PD-L2 expression in CHO-K1 cells.


feedback

Do you like the current new website?

Hate

Dislike

Neutral

Like

Love

*