CHO-K1/mouse HVEM Stable Cell Line
M00647 | |
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$8,500.00 | |
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Ask us a question |
M00647 | |
|
|
$8,500.00 | |
|
|
|
|
Ask us a question |
HVEM is found on the surface of various cell types, including hematopoietic and non-hematopoietic cells, and is expressed mainly in spleen, thymus, bone marrow, lung and intestines. It has been identified as a canonical TNF receptor, signaling through the TNF receptor-associated factors (TRAFs) leading to NFκB activation. Furthermore, in addition to acting as a signaling receptor, in binding to Ig superfamily members it acts as a ligand for these inhibitory receptors. Therefore, bidirectional signaling is possible for the HVEM-mediated signaling network, which can be involved in positive or negative immunological reactions under different contexts. |
TNFRSF14
Applications | Binding assay or use as immunogen |
Storage | Liquid nitrogen immediately upon receiving |
Species | Mouse |
Stability | 15 passages |
Freeze Medium | 95% complete growth medium, 5% DMSO |
Culture Medium | F12K, 10% FBS, 8 μg/ml Puromycin |