Ligand for the T-cell-specific cell surface receptor ICOS acts as a costimulatory signal for T-cell proliferation and cytokine secretion. It also induces B-cell proliferation and differentiation into plasma cells. It could also play an important role in mediating local tissue responses to inflammatory conditions, as well as modulating the secondary immune response by co-stimulating memory T-cell function.
B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L
|Freeze Medium||95% complete growth medium, 5% DMSO|
|Culture Medium||F12K, 10% FBS, 8 μg/ml Puromycin|
|Storage||Liquid nitrogen immediately upon receiving|
|Binding assay or use as immunogen|
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