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Home » Gene Synthesis & Molecular Biology Services » β-Amyloid (1-28)

β-Amyloid (1-28)

Synonyms Abeta 1-28
Description Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores and neuritic plaques and is also found as a deposit in neurofibrillary tangles. Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). Beta-amyloid peptide is generated from the beta-amyloid precursor protein (beta APP) in a two-step process.
Cas No 109770-29-8
Sequence
{ASP}{ALA}{GLU}{PHE}{ARG}{HIS}{ASP}{SER}{GLY}{TYR}{GLU}{VAL}
{HIS}{HIS}{GLN}{LYS}{LEU}{VAL}{PHE}{PHE}{ALA}{GLU}{ASP}{VAL}
{GLY}{SER}{ASN}{LYS}
Sequence Shortening DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Molecular Formula C145H209N41O46
Molecular Weight 3262.5

Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Anaspec Cat No Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys
Storage Store at -20°C.
Note Forms fibrils that have the same antigenic and structural features as the native Alzheimer Disease Amyloid filaments.


Cat. No.
Product Name
Price
RP10034-1
β-Amyloid (42-1) - 1 mg
$475.00
RP10034-0.5
β-Amyloid (42-1) - 0.5 mg
$285.00
RP10017-1
β-Amyloid (1-42), human - 1 mg
$214.00
RP10017-0.5
β-Amyloid (1-42), human - 0.5 mg
$119.00
RP10016-0.5
β-Amyloid (1-40), rat - 0.5 mg
$157.00
RP10013-1
β-Amyloid (1-42), rat - 1 mg
$309.00
RP10013-0.5
β-Amyloid (1-42), rat - 0.5 mg
$176.00
RP10008-5
β-Amyloid (25-35) - 5 mg
$209.00
RP10008-1
β-Amyloid (25-35) - 1 mg
$52.00
RP10004-1
β-Amyloid (1-40) - 1 mg
$190.00
RP10004-0.5
β-Amyloid (1-40) - 0.5 mg
$114.00
 
Gorbita CH. The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's beta-amyloid polypeptide. Chem. Commun(Camb). Jun 2006; 14(22): 2332-2334.

Song Y, et al. Comparison of MR images and histochemical localization of intra-arterially administered microglia surrounding beta-amyloid deposits in the rat brain. Histol. Histopathol. Jul 2006; 21(7): 705-711.

Park HY, et al. Modulation of neutrophil apoptosis by beta-amyloid proteins. Int. Immunopharmacol. Jul 2006; 6(7): 1061-1069.

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Cat. No. RP10002
Size
Price
0.5 mg $81.00