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Substance P (1-7)

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Substance P (1-7) is a fragment that gives depressor and bradycardic effects when applied to the nucleus tractus solitarius. A tritium-labeled aminoterminal heptapeptide of SP, 3H- SP(1-7), was synthesized, purified, and used to characterize the binding of a variety of fragments of SP and opioids in the mouse brain and spinal cord membranes. The characteristics of SP (1-7) binding sites are consistent with those expected for an SP N-terminal receptor.
RP10180
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Description

Substance P (1-7) is a fragment that gives depressor and bradycardic effects when applied to the nucleus tractus solitarius. A tritium-labeled aminoterminal heptapeptide of SP, 3H- SP(1-7), was synthesized, purified, and used to characterize the binding of a variety of fragments of SP and opioids in the mouse brain and spinal cord membranes. The characteristics of SP (1-7) binding sites are consistent with those expected for an SP N-terminal receptor.
Synonyms

SP

Overview
Cas No 68060-49-1
Sequence
{ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}
Sequence Shortening RPKPQQF
Molecular Formula C41H65N13O10
Molecular Weight 900.04
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Properties
Purity > 95%
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
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