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Melittin

*This product has been discontinued!*
This 26-residue polypeptide isolated from bee venom binds calmodulin in a Ca2+-dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50=5-7 mM) by binding to the catalytic domain in a Mg-ATP-sensitive manner.
RP10290
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Overview
Description This 26-residue polypeptide isolated from bee venom binds calmodulin in a Ca2+-dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50=5-7 mM) by binding to the catalytic domain in a Mg-ATP-sensitive manner.
Cas No 20449-79-0
Sequence
{GLY}{ILE}{GLY}{ALA}{VAL}{LEU}{LYS}{VAL}{LEU}{THR}{THR}{GLY}{LEU}{PRO}{ALA}{LEU}{ILE}{SER}{TRP}{ILE}{LYS}{ARG}{LYS}{ARG}{GLN}{GLN}-NH2
Sequence Shortening GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
Molecular Formula C131H229N39O31
C Terminal NH2
Molecular Weight 2846.46

Properties
Purity > 95%
Form Lyophilized
Storage Store at -20°C
Note Polypeptide from honey bee venom