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Catalog Products » PACAP (6-38), human, ovine, rat

PACAP (6-38), human, ovine, rat

Description PACAP (6-38) is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase. Ki values for the inhibition of the enzyme were 7nM and 150 nM, respectively. PACAP (6-38) caused a small but significant (approximately 20%) inhibition of the NANC relaxation due to electrical field stimulation (1 Hz or 10 Hz for 20 s). At these frequencies PACAP (6-38) caused no inhibition of the NANC relaxation in the presence of the P2 purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulphonic acid (or PPADS) plus the NO-synthase blocker NG-nitro-L-arginine; in preparations pretreated with L-NOARG alone, PACAP (6-38) retained its inhibitory effect.
Molecular Formula C182H300N56O45S1
C Terminal NH2
Molecular Weight 4024.76

Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Gmp Flag 0
Storage Store the peptide at -20°C.
Note This peptide is a potent agonist.

Cat. No. Product Name Quantity Price
PACAP-Related Peptide (PRP), human - 0.5 mg
PACAP (1-38), human, ovine, rat - 0.5 mg
PACAP (1-27), human, ovine, rat - 0.5 mg

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Cat. No. RP10338
Size Price
0.5 mg $133.00