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Catalog Products » Men 10376

Men 10376

*This product has been discontinued!*
Synonyms Neurokinin-2 receptor antagonist
Description Men 10376 is a potent and selective NK2 tachykinin receptor antagonist. MEN 10376 was devoid of significant agonist activity at i.v. doses (1-3 mumol/kg) which selectively antagonized the effects of an NK-2 agonist [beta-Ala8]-neurokinin A(4-10) (bladder contraction in rats, bronchoconstriction in guinea pigs) without affecting the response to an NK-1 agonist [Sar9]-substance P sulfone (hypotension, salivation and bladder contraction in rats, bronchoconstriction in guinea pigs).
Cas No 135306-85-3
Sequence
{ASP}{TYR}{d-TRP}{VAL}{d-TRP}{d-TRP}{LYS}-NH2
Sequence Shortening DYWVWWK-NH2
Molecular Formula C57H68N12O10
C Terminal NH2
Molecular Weight 1081.22

Purity > 95%
Storage Store at -20°C. Keep tightly closed.
Note




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