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Home » Gene Synthesis & Molecular Biology Services » C-telopeptide

C-telopeptide

Synonyms CTX
Description C-telopeptide(CTX) is an RIA based on monoclonal antibody raised against this 8-amino-acid sequence was developed. C-telopeptide(CTX) represents a valuable tool for assessing bone resorption. The study shows C-telopeptide(CTX) ELISA exhibited acceptable analytical performance and sufficient discriminatory power to show expected directional changes in the rate of bone resorption following ovariectomy, ovx plus estradiol or alendronate treatment, and administration of a calcium-deficient diet.
Sequence
{GLU}{LYS}{ALA}{HIS}{ASP}{GLY}{GLY}{ARG}
Sequence Shortening EKAHDGGR
Molecular Formula C34H56N14O13
Molecular Weight 868.9

Purity > 95%
Gmp Flag 0
Storage Store at -20°C.
Note


Garnero P, et al. Increased urinary type II collagen helical (Helix-II) and C-telopeptide(CTX-II) levels are independently associated with a rapidly destructive hip osteoarthritis. Ann. Rheum. Dis. Mar 2006.

Mazzuca SA, et al. Urinary Levels of Type II Collagen C-telopeptide Crosslink Are Unrelated to Joint Space Narrowing in Patients With Knee Osteoarthritis. Ann. Rheum. Dis. Dec 2005.

Alexandersen P, et al. Non-isomerized C-telopeptide fragments are highly sensitive markers for monitoring disease activity and treatment efficacy in Paget's disease of bone. J. Bone Miner. Res. Apr 2005; 20(4): 588-595.

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Cat. No. RP10566
Size
Price
0.5 mg $43.00