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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Thrombin Receptor Agonist

Thrombin Receptor Agonist

Description A synthetic thrombin receptor agonist peptide (TRP) of 7 residues (SFLLRNP) was found to be as effective as thrombin for Ca2+ mobilization, and both agonists induced Ca2+ release exclusively from internal stores. Thrombin stimulated tyrosine phosphorylation of several proteins of molecular mass 40,000 Da, 42,000 Da, 70,000 Da, 120,000 Da and 130,000 Da. There was a good correlation between thrombin-induced tyrosine phosphorylation of the latter three proteins and Ca2+ mobilization.
Cas No 137339-65-2
Sequence
{SER}{PHE}{LEU}{LEU}{ARG}{ASN}{PRO}{ASN}{ASP}{LYS}{TYR}{GLU}
{PRO}{PHE}
Sequence Shortening SFLLRNPNDKYEPF
Molecular Formula C81H118N20O23
Molecular Weight 1739.9

Purity > 95%
Gmp Flag 0
Anaspec Cat No Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe
Storage Store at -20°C.
Note


Smith SA, et al. Polyphosphate modulates blood coagulation and fibrinolysis. Proc.Natl.Acad.Sci.USA. Jan 2006; 103(4): 903-908.

Monroe DM, Hoffman M. What does it take to make the perfect clot. Arterioscler Thromb Vasc Biol. Jan 2006; 26(1): 41-48.

Suzuki-Inoue K, et al. A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2. Blood. Jan 2006; 107(2): 542-549.

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Cat. No. RP10623
Size
Price
1 mg $62.00