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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » γ-1-Melanocyte Stimulating Hormone (MSH), amide

γ-1-Melanocyte Stimulating Hormone (MSH), amide

Synonyms γ-1-MSH, amide;γ1-MSH; g-1-MSH; g1-MSH; gamma-1-MSH; gamma1-MSHγ-1-Melanocyte Stimulating Hormone; γ1-Melanocyte Stimulating Hormone; g-1-Melanocyte Stimulating Hormone; g1-Melanocyte Stimulating Hormone; gamma-1-Melanocyte Stimulating Hormone; gamma1-Melanocyte Stimulating Hormone
Description Gamma-MSH (Melanocyte Stimulating Hormone), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. Gamma-MSH peptides have low intrinsic melanotropic activity in mammalian melanoma cells; the specific pigmentary responses appear to be affected by the structure of the C-terminal portion.
Sequence
{TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}{PHE}-NH2
Sequence Shortening YVMGHFRWDRF-NH2
Molecular Formula C72H97N21O14S1
C Terminal NH2
Molecular Weight 1512.9

Purity > 95%
Gmp Flag 0
Storage Store the peptide at -20°C. Keep container tightly closed.
Note Gamma-1-MSH is derived from ACTH 1-13. Gamma-1-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. Gamma-1-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.


Cat. No.
Product Name
Price
RP17323
Melanotan (MT)-II - 5 mg
$82.00
RP10658-1
[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), amide - 1 mg
$66.00
RP10648
β-Melanocyte Stimulating Hormone (MSH), human - 1 mg
$90.00
RP10644-5
α-Melanocyte-Stimulating Hormone (MSH), amide - 5 mg
$57.00
RP10644-1
α-Melanocyte-Stimulating Hormone (MSH), amide - 1 mg
$24.00
 
Harmer SC, Bicknell AB. Role of gamma-MSH peptides in the regulation of adrenal steroidogenesis. Peptides. Oct 2005; 26(10): 1944-1951.

Mayorov AV, et al. Development of cyclic gamma-MSH analogues with selective hMC3R agonist and hMC3R/hMC5R antagonist activities. J. Med. Chem. Mar 2006; 49(6): 1946-1952.

Cai M, et al. Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues. J. Med. Chem. Mar 2005; 48(6): 1839-1848.

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Cat. No. RP10650
Size
Price
1 mg $52.00