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Home » Gene Synthesis & Molecular Biology Services » Mast Cell Degranulating Peptide

Mast Cell Degranulating Peptide

Synonyms MCDP
Description Mast Cell Degranulating Peptide (MCDP) is a neurotoxic agent isolated from bee venom. It produces a long-term potentiation in the hippocampus. Some studies show that Mast Cell Degranulating Peptide (MCDP) augments the release of excitatory and inhibitory transmitter by an action, which is independent of calcium influx, through voltage-dependent channels. Mast Cell Degranulating Peptide (MCDP) inhibited non-competitively the binding of both radiolabelled dendrotoxin and beta-bungarotoxin but with relatively low potency.
Cas No 32908-73-9
Sequence
{ILE}{LYS}{CYS}{ASN}{CYS}{LYS}{ARG}{HIS}{VAL}{ILE}{LYS}{PRO}{HIS}{ILE}{CYS}{ARG}{LYS}{ILE}{CYS}{GLY}{LYS}{ASN}-NH2
Sequence Shortening IKCNCKRHVIKPHICRKICGKN-NH2
Molecular Formula C110H192N40O24S4
C Terminal NH2
Disulfide Bridge Disulfide bridge: Cys3-Cys15, Cys5-Cys19
Molecular Weight 2587.22

Purity > 95%
Format Bridge 3-15,5-19
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Gmp Flag 0
Storage Before using, store the peptide in the DRY form at 0 - 5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
Note Mast Cell Degranulating Peptide (MCDP) is a very powerful anti-inflammatory peptide, and have potent neurotoxic action.




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Cat. No. RP10663
Size
Price
0.5 mg $119.00