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Phe-Met-Arg-Phe, amide

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Overview

Synonyms	F-M-R-F;-amide; Phe-Met-Arg-Phe amideMolluscan cardioexcitatory neuropeptide
Description	FMRF-amide belongs to Molluscan Cardioexcitatory Neuropeptide. This peptide appears to localize with neuropeptide Y in some regions of the brain. FMRF-amide inhibits Na⁺-Ca²⁺ exchange in cardiac sarcolemma vesicles. The neuropeptide FMRF-amide stimulated enzyme activity 7- to 8-fold (EC50, 1 mM) via receptors that were pharmacologically distinct from those for dopamine and serotonin. FMRF- amide augmented cyclic AMP levels in slices of gill tissue with a time course similar to that for adenylate cyclase activation.
Cas No	64190-70-1
Sequence	{PHE}{MET}{ARG}{PHE}-NH₂
Sequence Shortening	FMRF-NH₂
Molecular Formula	C₂₉H₄₂N₈O₄S₁
C Terminal	NH₂
Molecular Weight	598.76

Properties

Purity	> 95%
Solubility	Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Gmp Flag	0
Storage	Store at -20°C
Note

	Cat. No.	Product Name	Price
	RP13660	Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa - 1 mg	$25.00
	RP10814	Phe-Met-Arg-Phe - 5 mg	$24.00

Twan WH, et al. The presence and ancestral role of gonadotropin-releasing hormone in the reproduction of scleractinian coral, Euphyllia ancora. Endocrinology. Jan 2006; 147(1): 397-406.

Yamanaka N, et al. Identification of a novel prothoracicostatic hormone and its receptor in the silkworm Bombyx mori.J Biol Chem. Apr 2005; 280(15): 14684-14690.

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