|Synonyms||Endomorphin1; EM-1; EM1|
|Description||Endomorphin-1 (EM-1) is a recently isolated endogenous peptide having potent analgesic activity and high affinity and selectivity for the mu-opioid receptor. Endomorphin-1 activates G proteins and inhibits adenylyl cyclase activity in membrane preparations from cells stably expressing the mu opioid receptor, an effect reversed by the mu receptor antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2). However, endomorphin-1 appears to have no influence on cells stably expressing the delta opioid receptor.|
|Solubility||The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.|
|Anaspec Cat No||Tyr-Pro-Trp-Phe-NH2|
|Storage||Store the peptide at -20°C. Keep container tightly closed.|
|Note||Endomorphin-1 is a potent, selective endogenous μ opioid receptor agonist.|
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