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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Endomorphin-2

Endomorphin-2

Synonyms Endomorphin2
Description Endomorphin 2 is a potent, selective endogenous µ opioid receptor agonist. The physiological function of endomorphin-2 as a neurotransmitter or neuromodulator may cease through the rapid enzymatic process in the synapse of brain, as for other neuropeptides. Some results indicate that the administration of the endogenous µ-opioid ligand endomorphin-2, but not endomorphin-1, into the brain produces an antitussive effect via mainly naloxonazine-insensitive µ-opioid receptors, namely µ2-opioid receptors and partially kappa-opioid receptors.
Cas No 141801-26-5
Sequence
{TYR}{PRO}{PHE}{PHE}-NH2
Sequence Shortening YPFF-NH2
Molecular Formula C32H37N5O5
C Terminal NH2
Molecular Weight 571.67

Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Gmp Flag 0
Anaspec Cat No Tyr-Pro-Phe-Phe-NH2
Storage Store at -20°C. Keep tightly closed.
Note

  • Endomorphin-2
  • Endomorphin-2


Cat. No.
Product Name
Price
RP10925
Endomorphin-1 - 5 mg
$43.00
 
Viard E and Sapru HN, et al. Endomorphin-2 in the medial NTS attenuates the responses to baroreflex activation. Brain Res. Feb 2006; 1073-1074:365-373.

Botros M, et al. Endomorphin-1 and endomorphin-2 differentially interact with specific binding sites for substance P (SP) aminoterminal SP(1-7) in the rat spinal cord. Peptides. Apr 2006; 27(4):753-759.

Mizoguchi H, et al. Possible Involvement of Dynorphin A-(1-17) Release via {micro}1-Opioid Receptors in Spinal Antinociception by Endomorphin-2. J. Pharmacol. Exp. Ther. Apr 2006; 317(1): 362-368.

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Cat. No. RP10926
Size
Price
5 mg $43.00