Catalog Products » Corticotropin Releasing Factor, human, rat
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HPLC
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Corticotropin Releasing Factor, human, rat

*This product has been discontinued!*
Corticotropin-releasing factor (CRF) has been widely implicated as playing a major role in modulating the endocrine, autonomic, behavioral and immune responses to stress. Corticotropin Releasing Factor (CRF) is a hypothalamic peptide that releases adrenocorticotropic hormone (ACTH) and endorphin from the anterior pituitary. Corticotropin Releasing Factor (CRF) is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
RP10982
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Overview
Synonyms CRF, human, ratCorticotropin-releasing hormone (CRH)
Description Corticotropin-releasing factor (CRF) has been widely implicated as playing a major role in modulating the endocrine, autonomic, behavioral and immune responses to stress. Corticotropin Releasing Factor (CRF) is a hypothalamic peptide that releases adrenocorticotropic hormone (ACTH) and endorphin from the anterior pituitary. Corticotropin Releasing Factor (CRF) is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
Cas No 86784-80-7
Sequence
{SER}{GLU}{GLU}{PRO}{PRO}{ILE}{SER}{LEU}{ASP}{LEU}{THR}{PHE}{HIS}{LEU}{LEU}{ARG}{GLU}{VAL}{LEU}{GLU}{MET}{ALA}{ARG}{ALA}{GLU}{GLN}{LEU}{ALA}{GLN}{GLN}{ALA}{HIS}{SER}{ASN}{ARG}{LYS}{LEU}{MET}{GLU}{ILE}{ILE}-NH2
Sequence Shortening SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII-NH2
Molecular Formula C208H344N60O63S2
C Terminal NH2
Molecular Weight 4757.45
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Properties
Purity > 95%
Solubility Soluble in water (1 mg/ml), clear and colorless
Form Lyophilized
Storage Store at -20°C
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Citations
Erin Faught, et al. Coordinated action of CRH and cortisol shapes acute stress-induced behavioural response in zebrafish. Neuroendocrinology. (2021-01)