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Home » Gene Synthesis & Molecular Biology Services » Calcitonin Gene Related Peptide (CGRP) (8-37), rat

Calcitonin Gene Related Peptide (CGRP) (8-37), rat

Synonyms CGRP (8-37), rat
Description Calcitonin Gene Related Peptide (CGRP)(8-37) inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats. The present study was performed to explore the effect of CGRP(8-37) on the electrical stimulation-evoked discharge frequency of wide dynamic range (WDR) neurons in the dorsal horn of the spinal cord in rats. The results indicate that CGRP receptors play an important role in the transmission of presumed nociceptive information in the dorsal horn of the spinal cord.
Sequence
{VAL}{THR}{HIS}{ARG}{LEU}{ALA}{GLY}{LEU}{LEU}{SER}{ARG}{SER}{GLY}{GLY}{VAL}{VAL}{LYS}{ASP}{ASN}{PHE}{VAL}{PRO}{THR}{ASN}{VAL}{GLY}{SER}{GLU}{ALA}{PHE}-NH2
Sequence Shortening VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
Molecular Formula C138H224N42O41
C Terminal NH2
Molecular Weight 3127.6

Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Gmp Flag 0
Storage Before using, store the peptide in the DRY form at 0 - 5 °C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
Note a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.


Cat. No.
Product Name
Price
RP13606
Calcitonin (8-32), salmon - 0.2 mg
$138.00
RP11099-0.5
Calcitonin, salmon - 0.5 mg
$57.00
RP11095-0.5
Calcitonin Gene Related Peptide (CGRP), rat - 0.5 mg
$128.00
RP11092-0.5
Calcitonin Gene Related Peptide (CGRP) II, rat - 0.5 mg
$119.00
RP11089-0.5
Calcitonin Gene Related Peptide (CGRP) (8-37), human - 0.5 mg
$90.00
 
Kawase T, et al. Immature osteoblastic MG63 cells possess two calcitonin gene-related peptide receptor subtypes that respond differently to [Cys(Acm)(2,7)] calcitonin gene-related peptide and CGRP(8-37). Am. J. Physiol., Cell Physiol. Oct 2005; 289(4): C811-818.

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Cat. No. RP11090
Size
Price
0.5 mg $90.00