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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Bradykinin (1-5)

Bradykinin (1-5)

Description The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for certain biological activities. BK 1-5 is the smallest peptide that can inhibit α-thrombin-induced platelet aggregation and secretion and calcium mobilization. Bradykinin (1-5) also prevents α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.
Cas No 23815-89-6
Sequence
{ARG}{PRO}{PRO}{GLY}{PHE}
Sequence Shortening RPPGF
Molecular Formula C27H40N8O6
Molecular Weight 572.66

Purity > 95%
Gmp Flag 0
Storage Store the peptide at -20°C
Note

  • Bradykinin (1-5)
  • Bradykinin (1-5)


Cat. No.
Product Name
Price
RP13625
[Des-Arg9]-Bradykinin - 5 mg
$33.00
RP11135-5
Bradykinin (2-9) - 5 mg
$24.00
RP11133-5
Bradykinin (1-7) - 5 mg
$24.00
RP11132-5
Bradykinin (1-6) - 5 mg
$24.00
RP11130
Bradykinin (1-3) - 5 mg
$24.00
RP11129
Bradykinin - 10 mg
$24.00
 
Dielis AW, et al. The prothrombotic paradox of hypertension: role of the renin-angiotensin and kallikrein-kinin systems. Hypertension. Dec 2005; 46(6): 1236-1242.

Wu TJ, et al. Stimulation of luteinizing hormone-releasing hormone (LHRH) gene expression in GT1-7 cells by its metabolite, LHRH-(1-5). Endocrinology. Jan 2005; 146(1): 280-286.

Nieman MT, et al. Mapping the interaction of bradykinin 1-5 with the exodomain of human protease activated receptor 4. FEBS Lett. Jan 2005; 579(1): 25-29.

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Cat. No. RP11131
Size
Price
5 mg $24.00