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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Bombesin

Bombesin

Description Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. Bombesin has two known homologues in mammals called neuromedin B and gastrin releasing peptide. Bombesin works on the gastrointestinal tract neuroendocrine hormone and bombesin stimulates gastrin release from G cells. Bombesin activates three different G-protein coupled receptors known as BBR1 2 and 3. Bombesin also activates these receptors in the brain. Together with cholecystokinin bombesin is the second major source of negative feedback signals that stop eating behavior.
Cas No 31362-50-2
Sequence
GLP-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
Molecular Formula C71H110N24O18S1
C Terminal NH2
Molecular Weight 1619.9

Purity > 95%
Solubility 20 mg/ml CH3COOH 0.05 M clear, colorless
Gmp Flag 0
Storage Store at -20°C
Note

  • Bombesin
  • Bombesin


Xiao D, et al. Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells. Cancer Res. Nov 2005; 65(21): 9934-9942.

Li L, Wice BM. et al. Bombesin and nutrients independently and additively regulate hormone release from GIP/Ins cells. Am. J. Physiol. Endocrinol. Metab. Jan 2005; 288(1): E208-215.

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Cat. No. RP11157
Size
Price
1 mg $24.00
5 mg $90.00