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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Dermaseptin


Description Dermaseptins are antimicrobial peptides, strings of amino acids, or proteins, of various sizes and shapes. Dermaseptins were isolated from frog skin. Dermaseptin is a crucial part of the frog's immune system, inhibiting the growth of bacteria, protozoa and fungi. Dermaseptins are cationic (positively charged) and 27-34 residues in length. Dermaseptins adopt a largely K-helical conformation when binding to membranes. Like other antimicrobial peptides, dermaseptin is membrane-perturbing; however, unlike other antimicrobial peptides, dermaseptin rests on the surface of the bacterial membrane and does not insert.
Cas No 136212-91-4
Molecular Formula C152H257N43O44S2
Molecular Weight 3455.1

Purity > 95%
Gmp Flag 0
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
Note Highly potent antimicrobial activity against pathogenic fungi.

Shalev DE, et al. Consequences of N-acylation on structure and membrane binding properties of dermaseptin derivative K4-S4-(1-13). J. Biol. Chem. Apr 2006; 281(14): 9432-9438.

Rydlo T, et al. Antibacterial properties of dermaseptin S4 derivatives under extreme incubation conditions. Antimicrob. Agents Chemother. Feb 2006; 50(2): 490-497.

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Cat. No. RP11228
0.5 mg $157.00