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Magainin 2

*This product has been discontinued!*
Magainin II is a hemolytic and antibiotic peptide isolated from frog skin. Magainins are positively charged and amphiphatic. Magainin II is thought to preferentially bind to the anionic phospholipids abundant in bacterial membranes with the formation of dynamic peptide-lipid supramolecular pore and cell permeabilization. Binding to artificial neutral membranes has also been demonstrated.
RP11232
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Overview
Synonyms MagaininII; Magainin 2; Magainin2
Description Magainin II is a hemolytic and antibiotic peptide isolated from frog skin. Magainins are positively charged and amphiphatic. Magainin II is thought to preferentially bind to the anionic phospholipids abundant in bacterial membranes with the formation of dynamic peptide-lipid supramolecular pore and cell permeabilization. Binding to artificial neutral membranes has also been demonstrated.
Cas No 108433-95-0
Sequence
{GLY}{ILE}{GLY}{LYS}{PHE}{LEU}{HIS}{SER}{ALA}{LYS}{LYS}{PHE}
{GLY}{LYS}{ALA}{PHE}{VAL}{GLY}{GLU}{ILE}{MET}{ASN}{SER}
Sequence Shortening GIGKFLHSAKKFGKAFVGEIMNS
Molecular Formula C114H180N30O29S
Molecular Weight 2466.9
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Properties
Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out any smaller portion of the contents.
Form Lyophilized
Storage Store at -20°C. Keep container tightly closed. Store in a cool dry place.
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