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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Indolicidin

Indolicidin

Synonyms ILPWKWPWWPWRR-NH2
Description Indolicidin is a 13-residue peptide amide which was isolated and characterized from the cytoplasmic granules of bovine neutrophils, having potent antibacterial activity in vitro against bacteria and fungi. The primary structure of indolicidin is characterized by 5 tryptophan residues, which is the highest mole percentage of any known protein sequence and is unique among known endogenous antibacterial peptides.
Cas No 140896-21-5
Sequence
{ILE}{LEU}{PRO}{TRP}{LYS}{TRP}{PRO}{TRP}{TRP}{PRO}{TRP}{ARG}{ARG}-NH2
Sequence Shortening ILPWKWPWWPWRR-NH2
Molecular Formula C100H132N26O13
C Terminal NH2
Molecular Weight 1906.28

Purity > 95%
Gmp Flag 0
Storage Stored at -20°C. Keep tightly closed.
Note


Shaw JE, et al. Mechanisms of antimicrobial peptide action: Studies of indolicidin assembly at model membrane interfaces by in situ atomic force microscopy. J. Struct. Biol. Apr 2006; 154(1):42-58.

Xing H, et al. Increased pathogen resistance and yield in transgenic plants expressing combinations of the modified antimicrobial peptides based on indolicidin and magainin. Planta. Apr 2006; 223(5): 1024-1032.

Hsu CH, et al. Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA. Nucleic Acids Res. Jul 2005; 33(13): 4053-4064.

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Cat. No. RP11242
Size
Price
0.5 mg $71.00