Indolicidin

*This product has been discontinued!*

Indolicidin is a 13-residue peptide amide which was isolated and characterized from the cytoplasmic granules of bovine neutrophils, having potent antibacterial activity in vitro against bacteria and fungi. The primary structure of indolicidin is characterized by 5 tryptophan residues, which is the highest mole percentage of any known protein sequence and is unique among known endogenous antibacterial peptides.

Cat. No.	RP11242
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Overview Properties

Overview

Synonyms	ILPWKWPWWPWRR-NH2
Description	Indolicidin is a 13-residue peptide amide which was isolated and characterized from the cytoplasmic granules of bovine neutrophils, having potent antibacterial activity in vitro against bacteria and fungi. The primary structure of indolicidin is characterized by 5 tryptophan residues, which is the highest mole percentage of any known protein sequence and is unique among known endogenous antibacterial peptides.
Cas No	140896-21-5
Sequence	{ILE}{LEU}{PRO}{TRP}{LYS}{TRP}{PRO}{TRP}{TRP}{PRO}{TRP}{ARG}{ARG}-NH₂
Sequence Shortening	ILPWKWPWWPWRR-NH₂
Molecular Formula	C₁₀₀H₁₃₂N₂₆O₁₃
C Terminal	NH₂
Molecular Weight	1906.28

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Properties

Purity	> 95%
Form	Lyophilized
Storage	Stored at -20°C. Keep tightly closed.

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Citations

1. EbbensgaardAnna, et al. The Role of Outer Membrane Proteins and Lipopolysaccharides for the Sensitivity of to Antimicrobial Peptides. Front Microbiol. (2018)
2. EbbensgaardAnna, et al. Comparative Evaluation of the Antimicrobial Activity of Different Antimicrobial Peptides against a Range of Pathogenic Bacteria. PLoS ONE. (2015)