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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » A-779

A-779

Description A-779 is a potent and selective Ang (1-7) antagonist. A-779 antagonizes several actions of Ang (1-7), including A-779's antidiurectic effect and the changes in MAP produced by Ang (1-7) microinjection into the dorsomedial or ventrolateral medulla.
Sequence
{ASP}{ARG}{VAL}{TYR}{ILE}{HIS}{d-ALA}
Sequence Shortening DRVYIH{D-Ala}
Molecular Formula C39H60N12O11
Molecular Weight 873.0

Purity > 95%
Storage Store at -20°C.
Note


Santos RA, et al. Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension. May 2006; 47(5): 996-1002.

Iwata M, et al. Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effects. Am J Physiol Heart Circ Physiol. Dec 2005; 289(6): H2356-H2363.

Gonzalez-Villalobos R, et al. Megalin binds and internalizes angiotensin-(1-7). Am J Physiol Renal Physiol. May 2006; 290(5): F1270-F1275.

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Cat. No. RP11249
Size
Price
1 mg $43.00