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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » IRBP(161–180)

IRBP(161–180)

Description This peptide is a major pathogenic T-cell epitope (fragment 161–180). It is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).
Sequence
{SER}{GLY}{ILE}{PRO}{TYR}{ILE}{ILE}{SER}{TYR}{LEU}{HIS}{PRO}
{GLY}{ASN}{THR}{ILE}{LEU}{HIS}{VAL}{ASP}
Sequence Shortening SGIPYIISYLHPGNTILHVD
Molecular Formula C103H157N25O29
Molecular Weight 2209.51

Purity > 95%
Anaspec Cat No Ser-Gly-Ile-Pro-Tyr-Ile-Ile-Ser-Tyr-Leu-His-Pro-Gly-Asn-Thr-Ile-Leu-His-Val-Asp
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
Note

  • IRBP(161–180)
  • IRBP(161–180)


Stenkamp DL,et al. The interphotoreceptor retinoid-binding protein (IRBP) of the chicken (Gallus gallus domesticus). Mol. Vis. Sep 2005; 11: 833-845.

Grajewski RS, et al. Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity. J. Exp. Med. Apr 2006; 203(4): 851-856.

Merhi-Soussi F, et al. High Yield of Cells Committed to the Photoreceptor Fate from Expanded Mouse Retinal Stem Cells. Stem Cells. Apr 2006; Epub ahead of print.

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Cat. No. RP11841
Size
Price
5 mg $380.00