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Endothelin 1, human, porcine

*This product has been discontinued!*
This peptide is a potent vasoconstrictor, derived from endothelial cells. Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
RP12758
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Synonyms ET-1
Description This peptide is a potent vasoconstrictor, derived from endothelial cells. Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
Cas No 117399-94-7
Sequence
{CYS}{SER}{CYS}{SER}{SER}{LEU}{MET}{ASP}{LYS}{GLU}{CYS}{VAL}
{TYR}{PHE}{CYS}{HIS}{LEU}{ASP}{ILE}{ILE}{TRP}
Sequence Shortening CSCSSLMDKECVYFCHLDIIW
Molecular Formula C109H159N25O32S5
Disulfide Bridge Cys1-Cys15, Cys3-Cys11
Molecular Weight 2491.9
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Purity > 95%
Solubility The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Form Lyophilized
Storage Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
Note Potent vasoconstrictor peptide
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