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Home » Gene Synthesis & Molecular Biology Services » Endothelin 1, human, porcine

Endothelin 1, human, porcine

Synonyms ET-1
Description This peptide is a potent vasoconstrictor, derived from endothelial cells. Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
Cas No 117399-94-7
Sequence
{CYS}{SER}{CYS}{SER}{SER}{LEU}{MET}{ASP}{LYS}{GLU}{CYS}{VAL}
{TYR}{PHE}{CYS}{HIS}{LEU}{ASP}{ILE}{ILE}{TRP}
Sequence Shortening CSCSSLMDKECVYFCHLDIIW
Molecular Formula C109H159N25O32S5
Disulfide Bridge Disulfide bridges: 1-15 and 3-11
Molecular Weight 2491.9

Purity > 95%
Format Bridge 1-15,3-11
Solubility The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Anaspec Cat No Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp
Storage Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
Note Potent vasoconstrictor peptide

  • Endothelin 1, Human, Porcine
  • Endothelin 1, Human, Porcine


Ohkita M, et al. Differential effects of different statins on endothelin-1 gene expression and endothelial NOS phosphorylation in porcine aortic endothelial cells. Exp. Biol. Med.(Maywood). Jun 2006; 231(6): 772-776.

Jackson CD, et al. Expression and localization of human endothelin-converting enzyme-1 isoforms in symptomatic atherosclerotic disease and saphenous vein. Exp. Biol. Med.(Maywood). Jun 2006; 231(6): 794-801.

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Cat. No. RP12758
Size
Price
0.25 mg $142.00
1 mg $361.00