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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Enfuvirtide (T-20)

Enfuvirtide (T-20)

Synonyms ENF
Description 36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. N-terminal acetylated, C-terminal amide. Enfuvirtide is the first in this class to reach market approval. Fusion inhibitors block the last step in the three-step viral entry process consisting of attachment, co-receptor binding and fusion, thereby preventing viral capsid entry into the host cell. Enfuvirtide has a unique mechanism of action and high viral target specificity, and in clinical trials has been shown to exhibit both high efficacy and low toxicity. Enfuvirtide is a peptide mimetic of an essential region within viral envelope glycoprotein gp41 that functions by blocking gp41 structural rearrangements at a transitional pre-fusion conformation.
Cas No 159519-65-0
Molecular Formula C204H301N51O64
C Terminal NH2
N Terminal Ac
Molecular Weight 4491.88

Purity > 95%
Gmp Flag 0
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.

  • Enfuvirtide (T-20)
  • Enfuvirtide (T-20)

Mink M, Mosier SM et al. Impact of human immunodeficiency virus type 1 gp41 amino acid substitutions selected during enfuvirtide treatment on gp41 binding and antiviral potency of enfuvirtide in vitro. J Virol. Oct 2005;79(19):12447-54.

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Cat. No. RP17307
1 mg $165.00